Shimosato K, Tomita M, Ijiri I
J Chromatogr. 1986 Apr 25;377:279-86. doi: 10.1016/s0378-4347(00)80783-5.
A method for electrochemical determination of p-hydroxymethamphetamine and p-hydroxyamphetamine in human urine was investigated by column liquid chromatography. A rapid and simple extraction of these substances from urine was performed using a solid-phase extraction column. The detection limit for quantitation was approximately 50 pg for the metabolites. The simplicity and sensitivity of this method allows for analysis of these metabolites in the fields of toxicology and forensic medicine.
采用柱液相色谱法研究了一种电化学测定人尿中对羟基甲基苯丙胺和对羟基苯丙胺的方法。使用固相萃取柱对尿液中的这些物质进行了快速简便的萃取。这些代谢物的定量检测限约为50皮克。该方法的简便性和灵敏度使得在毒理学和法医学领域能够对这些代谢物进行分析。
