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氨曲南纸片药敏试验与琼脂稀释试验相关性的批判性评价。

Critical evaluation of amdinocillin disk susceptibility tests correlated with agar dilution tests.

作者信息

Barry A L

出版信息

J Clin Microbiol. 1986 May;23(5):983-5. doi: 10.1128/jcm.23.5.983-985.1986.

DOI:10.1128/jcm.23.5.983-985.1986
PMID:3711289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC268770/
Abstract

Tests with 10-micrograms amdinocillin disks were performed in parallel with agar dilution tests and three different ranges of inoculum density. A resistance breakpoint of less than or equal to 13 mm and an intermediate category of 14 to 16 mm are recommended. Susceptible strains provided zones greater than or equal to 17 mm in diameter, but many appeared to be resistant by the agar dilution methods if the inoculum exceeded 10(4) CFU per spot.

摘要

使用10微克氨比西林纸片进行的试验与琼脂稀释试验及三种不同接种物密度范围同时进行。推荐的耐药断点为小于或等于13毫米,中介类别为14至16毫米。敏感菌株产生的抑菌圈直径大于或等于17毫米,但如果每个点的接种物超过10⁴CFU,许多菌株通过琼脂稀释法似乎表现为耐药。

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本文引用的文献

1
Correlation of the results of antibiotic synergy and susceptibility testing in vitro with results in experimental mouse infections.抗生素体外协同作用和药敏试验结果与实验性小鼠感染结果的相关性。
Crit Rev Microbiol. 1982;10(1):1-76. doi: 10.3109/10408418209113505.
2
Influence of inoculum growth phase on microdilution susceptibility tests.接种物生长阶段对微量稀释药敏试验的影响。
J Clin Microbiol. 1983 Sep;18(3):645-51. doi: 10.1128/jcm.18.3.645-651.1983.
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Parenteral amdinocillin for treatment of complicated urinary tract infections.
Am J Med. 1983 Aug 29;75(2A):82-4. doi: 10.1016/0002-9343(83)90099-2.
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Review of clinical experience with amdinocillin monotherapy and comparative studies.氨曲南单药治疗的临床经验回顾及对比研究。
Am J Med. 1983 Aug 29;75(2A):72-81. doi: 10.1016/0002-9343(83)90098-0.
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Enhanced activity of beta-lactam antibiotics with amdinocillin in vitro and and in vivo.阿莫西林与氨比西林联用,β-内酰胺类抗生素的体外和体内活性增强。
Am J Med. 1983 Aug 29;75(2A):21-9. doi: 10.1016/0002-9343(83)90090-6.
6
Appraisal of disk sensitivity tests with mecillinam.美西林纸片药敏试验评估
Chemotherapy. 1981;27(2):106-13. doi: 10.1159/000237964.
7
Mecillinam, a novel penicillanic acid derivative with unusual activity against gram-negative bacteria.美西林,一种新型青霉素酸衍生物,对革兰氏阴性菌具有独特活性。
Antimicrob Agents Chemother. 1976 May;9(5):793-9. doi: 10.1128/AAC.9.5.793.
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Mecillinam--an amidino penicillin which acts synergistically with other beta-lactam compounds.美西林——一种脒基青霉素,可与其他β-内酰胺化合物协同作用。
J Antimicrob Chemother. 1977 Jul;3 Suppl B:43-52. doi: 10.1093/jac/3.suppl_b.43.
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Antibacterial activity of mecillinam.
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