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美国2019冠状病毒病(COVID-19)大流行期间瑞德西韦的使用及抗菌药物管理限制:一项横断面调查

Remdesivir use and antimicrobial stewardship restrictions during the coronavirus disease 2019 (COVID-19) pandemic in the United States: A cross-sectional survey.

作者信息

Mena Lora Alfredo J, Burgos Rodrigo, Borgetti Scott, Chaisson Lelia H, Bleasdale Susan C

机构信息

University of Illinois at Chicago, Chicago, Illinois.

出版信息

Antimicrob Steward Healthc Epidemiol. 2023 Mar 31;3(1):e63. doi: 10.1017/ash.2023.146. eCollection 2023.

DOI:10.1017/ash.2023.146
PMID:37113205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10127235/
Abstract

Deploying therapeutics for coronavirus disease 2019 (COVID-19) has proved challenging due to evolving evidence, supply shortages, and conflicting guideline recommendations. We conducted a survey on remdesivir use and the role of stewardship. Use differs significantly from guidelines. Hospitals with remdesivir restrictions were more guideline concordant. Formulary restrictions can be important for pandemic response.

摘要

由于证据不断演变、供应短缺以及指南建议相互冲突,为2019冠状病毒病(COVID-19)部署治疗方法已被证明具有挑战性。我们对瑞德西韦的使用情况及管理作用进行了一项调查。其使用情况与指南有显著差异。对瑞德西韦有限制规定的医院更符合指南。药品目录限制对疫情应对可能很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9807/10127235/94d3c63173dc/S2732494X23001468_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9807/10127235/94d3c63173dc/S2732494X23001468_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9807/10127235/94d3c63173dc/S2732494X23001468_fig1.jpg

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本文引用的文献

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Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.用于治疗新冠肺炎的抗病毒药物 repurposed - 世界卫生组织团结试验中期结果
N Engl J Med. 2021 Feb 11;384(6):497-511. doi: 10.1056/NEJMoa2023184. Epub 2020 Dec 2.
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应对百年一遇洪水的防洪堤:基于综合征的抗菌药物管理干预措施对2019冠状病毒病抗菌药物使用和耐药性的影响。
Antimicrob Steward Healthc Epidemiol. 2024 Sep 18;4(1):e131. doi: 10.1017/ash.2024.383. eCollection 2024.
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Antimicrobial stewardship and drug formulary restrictions during COVID-19: what is restricted and who decides?新冠疫情期间的抗菌药物管理与药品处方集限制:哪些药物受限,由谁来决定?
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Remdesivir for the Treatment of Covid-19 - Final Report.
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N Engl J Med. 2020 Nov 5;383(19):1813-1826. doi: 10.1056/NEJMoa2007764. Epub 2020 Oct 8.
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Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients with COVID-19.美国传染病学会关于2019冠状病毒病患者治疗与管理的指南
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