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在COVID-19大流行期间，抗菌药物管理部门对瑞德西韦处方集的限制对一家安全网社区医院的药物使用和成本的影响。

Impact of a remdesivir formulary restriction by antimicrobial stewardship on drug utilization and cost at a safety-net community hospital during the COVID-19 pandemic.

作者信息

Mena Lora Alfredo Jose, Huber Dylan, Li Ella, Lavani Romeen, Ali Mirza, Takhsh Eden, Burgos Rodrigo

机构信息

University of Illinois at Chicago, Chicago, IL, USA.

Saint Anthony Hospital, Chicago, IL, USA.

出版信息

Antimicrob Steward Healthc Epidemiol. 2024 Oct 7;4(1):e164. doi: 10.1017/ash.2024.438. eCollection 2023.

DOI:10.1017/ash.2024.438
PMID:39417044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11474786/
Abstract

Deploying novel COVID-19 therapies proved challenging amid rapidly evolving data, drug shortages, and conflicting guidelines. We established a remdesivir formulary restriction remdesivir to promote its evidence-based use. This intervention led to changes in remdesivir utilization patterns and cost savings. Formulary restrictions can play an important role in pandemic preparedness and response.

摘要

在数据快速变化、药品短缺和指南相互矛盾的情况下，部署新型新冠治疗方法颇具挑战。我们制定了一项关于瑞德西韦的处方集限制措施，以促进其基于证据的使用。这一干预措施导致了瑞德西韦使用模式的改变和成本节约。处方集限制在大流行防范和应对中可发挥重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c213/11474786/a204b9535021/S2732494X24004388_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c213/11474786/8186bc488c71/S2732494X24004388_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c213/11474786/a204b9535021/S2732494X24004388_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c213/11474786/8186bc488c71/S2732494X24004388_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c213/11474786/a204b9535021/S2732494X24004388_fig2.jpg

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本文引用的文献

1
Antimicrobial stewardship and drug formulary restrictions during COVID-19: what is restricted and who decides?新冠疫情期间的抗菌药物管理与药品处方集限制：哪些药物受限，由谁来决定？
Antimicrob Steward Healthc Epidemiol. 2023 Jun 30;3(1):e116. doi: 10.1017/ash.2023.205. eCollection 2023.
2
Remdesivir use and antimicrobial stewardship restrictions during the coronavirus disease 2019 (COVID-19) pandemic in the United States: A cross-sectional survey.美国2019冠状病毒病（COVID-19）大流行期间瑞德西韦的使用及抗菌药物管理限制：一项横断面调查
Antimicrob Steward Healthc Epidemiol. 2023 Mar 31;3(1):e63. doi: 10.1017/ash.2023.146. eCollection 2023.
3
The impact of an antimicrobial stewardship program restriction on remdesivir prescribing.
抗菌药物管理计划限制对瑞德西韦处方的影响。
Antimicrob Steward Healthc Epidemiol. 2022 Aug 31;2(1):e149. doi: 10.1017/ash.2022.290. eCollection 2022.
4
Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (September 2022).美国传染病学会关于 COVID-19 患者治疗和管理的指南（2022 年 9 月）。
Clin Infect Dis. 2024 Jun 27;78(7):e250-e349. doi: 10.1093/cid/ciac724.
5
Repurposed Antiviral Drugs for Covid-19 - Interim WHO Solidarity Trial Results.用于治疗新冠肺炎的抗病毒药物 repurposed - 世界卫生组织团结试验中期结果
N Engl J Med. 2021 Feb 11;384(6):497-511. doi: 10.1056/NEJMoa2023184. Epub 2020 Dec 2.
6
Remdesivir for the Treatment of Covid-19 - Final Report.瑞德西韦治疗 COVID-19 的疗效 - 最终报告。
N Engl J Med. 2020 Nov 5;383(19):1813-1826. doi: 10.1056/NEJMoa2007764. Epub 2020 Oct 8.
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