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采用蜂花粉绿色合成法制备的 Mg 纳米粒子系统(BP@MgNPs)的抗氧化、抗菌和神经毒性(在 Sh-Sy5y 细胞系中)特性。

Antioxidant, Antimicrobial, and Neurotoxicity (in Sh-Sy5y Cell Lines) Properties of Mg Nanoparticle System (BP@MgNPs) Prepared by Green Synthesis with Bee Pollen.

机构信息

Department of Nutrition and Dietetics, Faculty of Health Sciences, Bingöl University, 12000, Bingöl, Türkiye.

Department of Crop and Animal Production, Vocational School of Food, Agriculture and Livestock, Bingöl University, 12000, Bingöl, Türkiye.

出版信息

Chem Biodivers. 2023 Jun;20(6):e202201093. doi: 10.1002/cbdv.202201093. Epub 2023 Jun 5.

Abstract

Due to their distinct characteristics and possible uses in a variety of disciplines, nanoparticles have attracted a lot of attention recently. One area of interest is the synthesis of nanoparticles using natural sources such as bee pollen. The research aims to evaluate the usability of bee pollen extract-based magnesium nanoparticles (MgNPs). First, a palynological study was used to determine the plant source of bee pollen. The nanoparticle was characterized using scanning electron microscopy, energy dispersive X-ray analysis, transmission electron microscopy, X-ray diffractometry, and Fourier transform infrared spectroscopy. The results revealed cubic-shaped MgNPs with an average size range of 36-40 nm. Afterward, nanoparticles were evaluated for their antioxidant, antimicrobial, and neurotoxic properties. It was determined that the total antioxidant capacity, phenolic (TPC), flavonoid (TFC) content, DPPH radical scavenging, and antimicrobial activity of the nanoparticles were lower than pollen extract. At the same time, nanoparticles have less toxicity than bee pollen.

摘要

由于其独特的特性以及在多个学科领域的潜在应用,纳米粒子最近引起了广泛关注。其中一个研究领域是利用天然物质(如蜂花粉)合成纳米粒子。本研究旨在评估基于蜂花粉提取物的镁纳米粒子(MgNPs)的可用性。首先,利用孢粉学研究确定了蜂花粉的植物来源。然后使用扫描电子显微镜、能谱分析、透射电子显微镜、X 射线衍射和傅里叶变换红外光谱对纳米粒子进行了表征。结果表明,MgNPs 呈立方形状,平均粒径范围为 36-40nm。随后,评估了纳米粒子的抗氧化、抗菌和神经毒性特性。结果表明,纳米粒子的总抗氧化能力、多酚(TPC)、类黄酮(TFC)含量、DPPH 自由基清除活性和抗菌活性均低于花粉提取物。同时,纳米粒子的毒性也低于蜂花粉。

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