Bitgood J J, Whitley R D
J Hered. 1986 Mar-Apr;77(2):123-5. doi: 10.1093/oxfordjournals.jhered.a110183.
A Z-linked recessive mutation in the domestic fowl is reported that results in a keratoglobus of both eyes. It does not appear to have any effect on the vision of affected individuals. The keratoglobus is not noticeable at hatching, but becomes obvious by 5-6 weeks of age. The mutant has been designated pop-eye, gene symbol pop. Initial studies suggest linkage with the late feathering (K) locus, and with the NM 7092 t (Z;1) translocation, which had previously been shown to be closely linked with Z-linked silver (S). There appear to be no other detrimental effects associated with this mutant. Preliminary analysis of T3 and T4 thyroid hormone levels do not indicate any thyroid malfunction.
据报道,家鸡中一种Z连锁隐性突变会导致双眼角膜扩张。这似乎对受影响个体的视力没有任何影响。角膜扩张在孵化时并不明显,但在5至6周龄时变得明显。该突变体已被命名为突眼,基因符号为pop。初步研究表明它与迟羽(K)位点以及NM 7092 t(Z;1)易位连锁,之前已证明NM 7092 t(Z;1)易位与Z连锁银色(S)紧密连锁。似乎没有与该突变体相关的其他有害影响。对T3和T4甲状腺激素水平的初步分析并未表明存在任何甲状腺功能障碍。