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突眼症:鸡的一种遗传性Z连锁角膜膨出症。

Pop-eye: an inherited Z-linked keratoglobus in the chicken.

作者信息

Bitgood J J, Whitley R D

出版信息

J Hered. 1986 Mar-Apr;77(2):123-5. doi: 10.1093/oxfordjournals.jhered.a110183.

DOI:10.1093/oxfordjournals.jhered.a110183
PMID:3711638
Abstract

A Z-linked recessive mutation in the domestic fowl is reported that results in a keratoglobus of both eyes. It does not appear to have any effect on the vision of affected individuals. The keratoglobus is not noticeable at hatching, but becomes obvious by 5-6 weeks of age. The mutant has been designated pop-eye, gene symbol pop. Initial studies suggest linkage with the late feathering (K) locus, and with the NM 7092 t (Z;1) translocation, which had previously been shown to be closely linked with Z-linked silver (S). There appear to be no other detrimental effects associated with this mutant. Preliminary analysis of T3 and T4 thyroid hormone levels do not indicate any thyroid malfunction.

摘要

据报道,家鸡中一种Z连锁隐性突变会导致双眼角膜扩张。这似乎对受影响个体的视力没有任何影响。角膜扩张在孵化时并不明显,但在5至6周龄时变得明显。该突变体已被命名为突眼,基因符号为pop。初步研究表明它与迟羽(K)位点以及NM 7092 t(Z;1)易位连锁,之前已证明NM 7092 t(Z;1)易位与Z连锁银色(S)紧密连锁。似乎没有与该突变体相关的其他有害影响。对T3和T4甲状腺激素水平的初步分析并未表明存在任何甲状腺功能障碍。

相似文献

1
Pop-eye: an inherited Z-linked keratoglobus in the chicken.突眼症:鸡的一种遗传性Z连锁角膜膨出症。
J Hered. 1986 Mar-Apr;77(2):123-5. doi: 10.1093/oxfordjournals.jhered.a110183.
2
Hereditary congenital baldness: a sex-linked trait in the domestic fowl.
J Hered. 1989 Nov-Dec;80(6):493-6. doi: 10.1093/oxfordjournals.jhered.a110910.
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Close linkage relationship of the Z-linked pop-eye and silver plumage color loci in the chicken.
Poult Sci. 1996 Sep;75(9):1067-8. doi: 10.3382/ps.0751067.
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Linkage relationships of the Z-linked silver, slow feathering, and pop-eye loci.Z染色体连锁的银色、慢羽和突眼基因座的连锁关系。
Poult Sci. 1999 Aug;78(8):1100-1. doi: 10.1093/ps/78.8.1100.
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Tardy feathering locus (t) located on chromosome 1 in the chicken.
J Hered. 1987 Sep-Oct;78(5):329-30. doi: 10.1093/oxfordjournals.jhered.a110398.
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An autosomal recessive blind mutant in the chicken.鸡的一种常染色体隐性失明突变体。
Poult Sci. 1980 Oct;59(10):2179-81. doi: 10.3382/ps.0592179.
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Additional linkage relationships within the Z chromosome of the chicken.鸡Z染色体内的其他连锁关系。
Poult Sci. 1985 Dec;64(12):2234-8. doi: 10.3382/ps.0642234.
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Analysis of the rdd locus in chicken: a model for human retinitis pigmentosa.鸡视网膜变性(rdd)位点分析:人类视网膜色素变性的一个模型
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White skin: a Z-linked recessive mutation in the fowl.白色皮肤:家禽中的一种Z连锁隐性突变。
J Hered. 1981 Mar-Apr;72(2):139-40. doi: 10.1093/oxfordjournals.jhered.a109450.
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Genetic map of the chicken Z chromosome using random amplified polymorphic DNA (RAPD) markers.利用随机扩增多态性DNA(RAPD)标记构建鸡Z染色体遗传图谱。
Genomics. 1993 Apr;16(1):224-30. doi: 10.1006/geno.1993.1163.

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