Department of Medicine, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Postgrad Med J. 2023 Aug 22;99(1175):954-961. doi: 10.1136/pmj-2022-141864.
Evaluation of suspected rheumatic disease is a significant challenge due to overlapping and sometimes non-specific clinical features. Most laboratory tests in rheumatic disease have incomplete sensitivity and specificity, leading to positive results without disease and negative results despite disease presence. Therefore, judicious ordering and correct interpretation of laboratory testing in rheumatology is critical in order to provide high-value care. Herein we review laboratory testing in rheumatology in the context of a framework for approaching rheumatic disease.
评估疑似风湿性疾病是一项重大挑战，因为这些疾病的临床特征常常重叠，且有时并不具有特异性。风湿性疾病的大多数实验室检测都存在不完全的灵敏度和特异性，这导致了即使存在疾病，检测结果也可能为阳性，而在没有疾病的情况下，检测结果也可能为阴性。因此，在风湿科中，明智地选择和正确地解读实验室检测对于提供高价值的医疗服务至关重要。本文旨在通过风湿性疾病的评估框架，来对风湿科的实验室检测进行综述。
