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干眼的系统性研究。

Systemic investigations in dry eye disease.

机构信息

Department of Cornea and Refractive Surgery, Narayana Nethralaya Eye Hospital, Bengaluru, Karnataka, India.

Government Medical College, Paripally, Kollam District, Kerala, India.

出版信息

Indian J Ophthalmol. 2023 Apr;71(4):1326-1331. doi: 10.4103/IJO.IJO_3003_22.

DOI:10.4103/IJO.IJO_3003_22
PMID:37026264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10276668/
Abstract

The incidence of dry eye disease has increased manifold in the past few years with more patients presenting with these complaints to our clinics every day. In the more severe forms of disease, it is important to evaluate for any systemic association which could be driving the disease such as in Sjogren's syndrome. Understanding the possible varied etiopathogenesis and knowing when to evaluate, form an important part of treating this condition effectively. In addition, it is sometimes confusing as to which investigations to order and how to prognosticate the disease in these situations. This article simplifies this into an algorithmic approach with insights from the ocular and systemic point of view.

摘要

近年来,干眼症的发病率呈数倍增长,每天都有更多的患者到我们的诊所就诊并主诉这些症状。在疾病的更严重形式中,评估任何可能导致疾病的系统性关联非常重要,如干燥综合征。了解可能的不同病因发病机制并知道何时进行评估,是有效治疗这种疾病的重要组成部分。此外,在这些情况下,有时会混淆要进行哪些检查以及如何预测疾病的预后。本文从眼部和系统性角度出发,将其简化为一种算法方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f5/10276668/577a8855b609/IJO-71-1326-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f5/10276668/577a8855b609/IJO-71-1326-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/31f5/10276668/577a8855b609/IJO-71-1326-g001.jpg

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本文引用的文献

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Approach to laboratory ordering and interpretation in rheumatology.风湿病学中的实验室检验申请与解读方法。
Postgrad Med J. 2023 Aug 22;99(1175):954-961. doi: 10.1136/pmj-2022-141864.
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Prevalence of dry eye in patients with systemic lupus erythematosus: a meta-analysis.系统性红斑狼疮患者干眼的患病率:一项荟萃分析。
BMJ Open. 2021 Sep 29;11(9):e047081. doi: 10.1136/bmjopen-2020-047081.
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Study of Factors Influencing Dry Eye in Rheumatoid Arthritis.类风湿关节炎干眼影响因素的研究
J Ophthalmol. 2020 Aug 8;2020:5768679. doi: 10.1155/2020/5768679. eCollection 2020.
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Association between vitamin D and dry eye disease: A systematic review and meta-analysis of observational studies.维生素 D 与干眼症的相关性:一项观察性研究的系统评价和荟萃分析。
Cont Lens Anterior Eye. 2020 Oct;43(5):418-425. doi: 10.1016/j.clae.2020.03.001. Epub 2020 Mar 10.
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Dry eye in rheumatoid arthritis: relation to disease activity.类风湿关节炎中的干眼:与疾病活动度的关系。
Immunol Med. 2020 Jun;43(2):92-97. doi: 10.1080/25785826.2020.1729597. Epub 2020 Feb 23.
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Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye.异常的泪液伤害感受相关因子、角膜树突状细胞密度和蒸发性干眼的维生素 D 水平。
Invest Ophthalmol Vis Sci. 2019 Jun 3;60(7):2532-2542. doi: 10.1167/iovs.19-26914.
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Laboratory tests in rheumatology: A rational approach.风湿病学实验室检查:一种合理的方法。
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8
Calcitriol inhibits ROS-NLRP3-IL-1β signaling axis via activation of Nrf2-antioxidant signaling in hyperosmotic stress stimulated human corneal epithelial cells.骨化三醇通过激活 Nrf2-抗氧化信号抑制高渗应激刺激的人角膜上皮细胞中的 ROS-NLRP3-IL-1β 信号轴。
Redox Biol. 2019 Feb;21:101093. doi: 10.1016/j.redox.2018.101093. Epub 2018 Dec 26.
9
Current concepts on Sjögren's syndrome - classification criteria and biomarkers.干燥综合征的当前概念——分类标准和生物标志物
Eur J Oral Sci. 2018 Oct;126 Suppl 1(Suppl Suppl 1):37-48. doi: 10.1111/eos.12536.
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