Program in Neuroscience, Graduate Program in Life Sciences, School of Medicine, University of Maryland, Baltimore, Maryland; Center to Advance Chronic Pain Research, University of Maryland, Baltimore, Maryland.
Center to Advance Chronic Pain Research, University of Maryland, Baltimore, Maryland; Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, Maryland.
J Pain. 2023 Sep;24(9):1617-1632. doi: 10.1016/j.jpain.2023.04.010. Epub 2023 Apr 28.
Pain catastrophization (PC), involving rumination, magnification, and helplessness, can be viewed as a coping strategy associated with chronic pain. PC is considered a driving force in mediating pain-related outcomes, but it is still unclear whether PC mediates the relationship between psychological and sociodemographic factors with chronic pain when considered in a single model. Using baseline data from a parent study, this study examined the effect of positive and negative psychological and sociodemographic factors on pain severity, interference, and jaw limitation mediated by the PC dimensions in a sample of 397 temporomandibular disorder (TMD) participants using structural equation modeling (SEM). SEM revealed that pain severity regressed on age, sex, education, and income; interference regressed on positive and negative psychological factors, education, and income; and jaw limitation regressed on age. The PC dimensions did not individually mediate these relationships. Although they jointly mediated the relationships between negative psychological factors and pain severity and between age and pain interference, the effect size was small, suggesting that PC is not a critical factor in mediating TMD pain outcomes. Reducing negative cognitions, not just PC, may be of greatest benefit to the most vulnerable TMD populations. PERSPECTIVE: This study examines sociodemographic and psychological factors that affect orofacial pain, finding that the pain catastrophizing dimensions do not mediate these relationships. Understanding which factors most strongly affect pain outcomes will help identify targets for intervention to produce the greatest benefit for the most vulnerable persons suffering from pain.
疼痛灾难化(PC),包括反刍思维、夸大和无助感,可以被视为与慢性疼痛相关的一种应对策略。PC 被认为是介导与疼痛相关结果的驱动力,但当在单一模型中考虑心理和社会人口因素时,PC 是否介导这些因素与慢性疼痛之间的关系仍不清楚。本研究使用一项父母研究的基线数据,通过结构方程模型(SEM),在 397 名颞下颌关节紊乱(TMD)患者样本中,考察了积极和消极心理及社会人口因素对疼痛严重程度、干扰和下颌限制的影响,这些因素通过 PC 维度进行介导。SEM 显示,疼痛严重程度与年龄、性别、教育程度和收入有关;干扰与积极和消极心理因素、教育程度和收入有关;下颌限制与年龄有关。PC 维度并未单独介导这些关系。尽管它们共同介导了消极心理因素与疼痛严重程度之间以及年龄与疼痛干扰之间的关系,但效应大小较小,表明 PC 不是介导 TMD 疼痛结果的关键因素。减少消极认知,而不仅仅是 PC,可能对最脆弱的 TMD 人群最有益。观点:本研究考察了影响口腔颌面部疼痛的社会人口和心理因素,发现疼痛灾难化维度不能介导这些关系。了解哪些因素对疼痛结果的影响最大,将有助于确定干预目标,为最脆弱的疼痛患者带来最大的益处。