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疼痛灾难化在老年亚洲移民慢性疼痛患者抑郁与疼痛严重程度及干扰之间关联中的中介作用

The Mediating Role of Pain Catastrophizing on the Association Between Depression and Pain Severity and Interference Among Elderly Asian Immigrants with Chronic Pain.

作者信息

Kim Hee Jun, Park Hyunjeong, Juon Hee-Soon

机构信息

Research Institute of Nursing Science, College of Nursing, Ajou University, Suwon, 16499, Republic of Korea.

Department of Nursing, Towson University, Towson, MD, 21252, USA.

出版信息

J Pain Res. 2021 Mar 12;14:737-745. doi: 10.2147/JPR.S304440. eCollection 2021.

Abstract

PURPOSE

The association between depression and chronic pain is well established. However, few studies have examined the pathways from depression to chronic pain. The present cross-cultural study aimed to test the mediating effects of pain catastrophizing on associations between depression and chronic pain (eg, pain severity, pain intensity) among Korean American elderly.

PATIENTS AND METHODS

A total of 132 elderly Korean Americans with chronic pain were recruited from elderly daycare centers and Korean ethnic churches in the community. For mediation analyses, structural equation modeling with full information maximum likelihood estimation method was used. The bias-corrected bootstrap confidence interval (CI) method for inferential tests of the indirect effects was also conducted in mediation analysis.

RESULTS

The results indicated that the proportion of comorbid depression and chronic pain was 45.7%. Elderly Korean Americans with depression scored higher in pain severity, pain interference, and pain catastrophizing than those without depression. Pain catastrophizing was found to have a significant mediating effect on the relationship between depression and pain severity (indirect effect = 0.147, Bootstrap 95% CI = [0.079, 0.226]), controlling for demographic covariates, comorbidities and pain area. Pain catastrophizing also mediated the relationship between depression and pain interference (indirect effect =0.164, Bootstrap 95% CI = [0.097, 0.244]), controlling for the covariates.

CONCLUSION

These findings add to the literature by providing evidence that pain catastrophizing plays a role in high levels of pain severity and pain interference comorbid chronic pain and depression in Asian elderly immigrants. Appropriate culturally tailored programs to redirect pain catastrophizing cognitive process should be developed and provided for elderly Asian Americans to reduce chronic pain disparity.

摘要

目的

抑郁症与慢性疼痛之间的关联已得到充分证实。然而,很少有研究探讨从抑郁症到慢性疼痛的途径。本跨文化研究旨在检验灾难化思维在韩裔美国老年人抑郁症与慢性疼痛(如疼痛严重程度、疼痛强度)之间的关联中所起的中介作用。

患者与方法

从社区的老年日托中心和韩裔教会招募了132名患有慢性疼痛的韩裔美国老年人。对于中介分析,使用了基于完全信息最大似然估计方法的结构方程模型。中介分析中还采用了偏差校正的自助法置信区间(CI)方法对间接效应进行推断检验。

结果

结果表明,抑郁症与慢性疼痛共病的比例为45.7%。患有抑郁症的韩裔美国老年人在疼痛严重程度、疼痛干扰和灾难化思维方面的得分高于无抑郁症者。在控制人口统计学协变量、共病情况和疼痛部位后,发现灾难化思维在抑郁症与疼痛严重程度之间的关系中具有显著的中介作用(间接效应=0.147,自助法95%CI=[0.079,0.226])。在控制协变量后,灾难化思维也介导了抑郁症与疼痛干扰之间的关系(间接效应=0.164,自助法95%CI=[0.097,0.244])。

结论

这些发现为灾难化思维在亚洲老年移民中高水平的疼痛严重程度和疼痛干扰合并慢性疼痛与抑郁症中发挥作用提供了证据,从而丰富了文献。应为美国亚裔老年人制定并提供适当的、符合文化特点的方案,以重新引导灾难化思维的认知过程,减少慢性疼痛差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/46db/7966355/91d133ec13e5/JPR-14-737-g0001.jpg

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