Runikhina Sofiya A, Afanasyev Oleg I, Kuchuk Ekaterina A, Perekalin Dmitry S, Jagadeesh Rajenahally V, Beller Matthias, Chusov Denis
A.N. Nesmeyanov Institute of Organoelement Compounds of Russian Academy of Sciences Vavilova St. 28 Moscow 119991 Russian Federation
Plekhanov Russian University of Economics Stremyanny per. 36 Moscow 117997 Russian Federation.
Chem Sci. 2023 Mar 31;14(16):4346-4350. doi: 10.1039/d3sc00257h. eCollection 2023 Apr 26.
Converter gas is a large scale waste product that is usually burned to carbon dioxide and contributes to the world emission of greenhouse gases. Herein we demonstrate that instead of burning the converter gas can be used as a reducing agent in organic reactions to produce valuable pharmaceuticals and agrochemicals. In particular, amide-based selected drug molecules have been synthesized by a reaction of aromatic nitro compounds and carboxylic acids in the presence of converter gas. In addition, we showed that this gas can also be conveniently utilized to carryout classical reductive amination reaction.
转炉气是一种大规模的废弃物，通常会被燃烧成二氧化碳，从而导致全球温室气体排放增加。在此，我们证明，转炉气无需燃烧，而是可以用作有机反应中的还原剂，用于生产有价值的药物和农用化学品。具体而言，在转炉气存在的情况下，通过芳香族硝基化合物与羧酸反应，已经合成了基于酰胺的特定药物分子。此外，我们还表明，这种气体还可方便地用于进行经典的还原胺化反应。
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