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早期生活中的抗生素与儿童肥胖:酵母益生菌作为调节肠道微生物群的一种策略

Early-Life Antibiotics and Childhood Obesity: Yeast Probiotics as a Strategy to Modulate Gut Microbiota.

作者信息

Rawat Sanjiv Singh, Narain Nigam P, Marathe Sanjay M, Sonawale Sourabh B, Veligandla Krishna C

机构信息

Pediatrics, Child Care Hospital, Indore, IND.

Pediatrics, Patna Medical College, Patna, IND.

出版信息

Cureus. 2023 Mar 28;15(3):e36795. doi: 10.7759/cureus.36795. eCollection 2023 Mar.

Abstract

This study aimed to review the existing literature to investigate the potential link between early-life antibiotic use and being overweight or obese in children. PubMed, Web of Science, Embase, Google Scholar, and Cochrane Library were searched to identify studies published until August 2021 that assessed the relationship between early-childhood antibiotic use and measures of body mass index. The studies included children aged 0-18 years. Only cohort studies were taken into consideration. Studies published in languages other than English were excluded. Antibiotic usage in early life may increase the risk of obesity in children and the addition of yeast probiotics, such as , to antibiotic prescription can serve as a potential option to mitigate this risk.

摘要

本研究旨在回顾现有文献,以调查儿童早期使用抗生素与超重或肥胖之间的潜在联系。检索了PubMed、科学网、Embase、谷歌学术和Cochrane图书馆,以确定截至2021年8月发表的评估儿童早期抗生素使用与体重指数测量值之间关系的研究。这些研究包括0至18岁的儿童。仅纳入队列研究。排除非英文发表的研究。儿童早期使用抗生素可能会增加肥胖风险,在抗生素处方中添加酵母益生菌(如 )可作为降低这种风险的潜在选择。

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