Swisher Matthew W, Dolendo Isabella M, Sztain Jacklynn F, Alexander Brenton S, Tsuda Paige S, Anger Jennifer T, Said Engy T
Anesthesiology, University of California San Diego, La Jolla, USA.
Urology, University of California San Diego, La Jolla, USA.
Cureus. 2023 Mar 27;15(3):e36748. doi: 10.7759/cureus.36748. eCollection 2023 Mar.
Background Gender-affirming pelvic surgery (GAPS) can be associated with significant postoperative pelvic pain. Given the lack of available peripheral nerve blocks to the perineum, intrathecal morphine (ITM) injection could offer a potent analgesic modality for this patient population. No prior studies to date have been performed examining the analgesic effects of intrathecal morphine for these patients. Methods This retrospective case-control study aims to understand the postoperative analgesic effects of intrathecal morphine for these patients with a historical comparison group of patients who did not receive intrathecal morphine. Results Fourteen patients presented for gender-affirming pelvic surgery over an eight-month period at a single institution and were offered intrathecal morphine for postoperative analgesia. Their analgesic results were compared to a similar historical group of 13 patients who were not offered or declined intrathecal morphine. Conclusions Intrathecal morphine injection is a potent analgesic modality for patients presenting for gender-affirming pelvic surgery.
背景 性别肯定性盆腔手术（GAPS）可能与显著的术后盆腔疼痛相关。鉴于缺乏可用于会阴的外周神经阻滞方法，鞘内注射吗啡（ITM）可为该患者群体提供一种有效的镇痛方式。迄今为止，尚无先前的研究探讨鞘内注射吗啡对这些患者的镇痛效果。方法 这项回顾性病例对照研究旨在通过与未接受鞘内注射吗啡的历史对照组患者进行比较，了解鞘内注射吗啡对这些患者的术后镇痛效果。结果 在单一机构的八个月期间，有14例患者接受了性别肯定性盆腔手术，并接受了鞘内注射吗啡用于术后镇痛。他们的镇痛结果与13例未接受或拒绝鞘内注射吗啡的类似历史组患者进行了比较。结论 鞘内注射吗啡是为接受性别肯定性盆腔手术的患者提供的一种有效的镇痛方式。
