Department of Infectious Disease, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
Department of General Surgery, First Medical Center of Chinese PLA General Hospital, Beijing 100853, China.
J Immunol Res. 2023 Apr 19;2023:4835710. doi: 10.1155/2023/4835710. eCollection 2023.
Idiopathic pulmonary fibrosis (IPF) is a disease with significant morbidity, progressive deterioration of lung function till death, and lack of effective treatment options. This study aims to explore the global research trends in IPF and immune response to predict the research hotspot in the future. . All related publications on IPF and immune response since the establishment of diagnostic criteria for IPF were retrieved using the Web of Science (WOS) database. VOSviewer, GraphPad Prism 6, CiteSpace version 5.6. R5 64-bit, and a bibliometrics online platform were used to extract and analyze the trends in relevant fields.
From March 1, 2000, to September 30, 2022, a total of 658 articles with 25,126 citations met the inclusion criteria. The United States ranked first in number of publications ( = 217), number of citations ( = 14,745), and H-index (62). China ranked second in publications ( = 124) and seventh and fifth for citation frequency and H-index, respectively. The (impact factor = 30.528) published the most articles in the field. The author Kaminski N. from the United States was the most influential author with 26 publications and an H-index of 24. Among the 52 keywords that co-occurred at least 20 times, the main keywords were concentrated in "Inflammation related" and "Biomarker related" clusters. "biomarker" (AAY 2018.64, 25 times) was a newly emerged keyword.
The United States has an unequivocal advantage in IPF and immunization, but China shows a faster developing trend. The should be prioritized for leading articles. This study indicates that exploration of ideal immune-related biomarkers to provide evidence for the clinical work of IPF might be a hotspot in the near future.
特发性肺纤维化（IPF）是一种发病率高的疾病，其肺部功能会逐渐恶化直至死亡，且目前缺乏有效的治疗方法。本研究旨在探索 IPF 及其免疫反应的全球研究趋势，预测未来的研究热点。 从 IPF 诊断标准建立以来，使用 Web of Science（WOS）数据库检索了与 IPF 和免疫反应相关的所有出版物。使用 VOSviewer、GraphPad Prism 6、CiteSpace 版本 5.6、64 位 R5 和一个文献计量学在线平台提取和分析相关领域的趋势。
从 2000 年 3 月 1 日至 2022 年 9 月 30 日，共纳入 658 篇文章，引用次数为 25126 次。美国在发文量（ = 217）、被引次数（ = 14745）和 H 指数（62）方面排名第一。中国在发文量（ = 124）排名第二，在被引频次和 H 指数方面分别排名第七和第五。《美国呼吸与危重病医学杂志》（impact factor = 30.528）发表的相关文章最多。美国的作者 Kaminski N. 发文量最多（26 篇），H 指数为 24。在至少共同出现 20 次的 52 个关键词中，主要关键词集中在“炎症相关”和“生物标志物相关”两个聚类中。“生物标志物”（AAY 2018.64，25 次）是一个新出现的关键词。
美国在 IPF 和免疫方面具有明显优势，但中国呈现出更快的发展趋势。应优先考虑《美国呼吸与危重病医学杂志》发表的文章。本研究表明，探索理想的免疫相关生物标志物为 IPF 的临床工作提供证据可能是近期的一个热点。
