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VEST III试验——我们应该支持静脉移植物吗？

VEST III trial - should we support the vein grafts?

作者信息

Narayan Pradeep

机构信息

Department of Cardiac Surgery, Rabindranath Tagore International Institute of Cardiac Sciences, Narayana Health, 124, EM Bypass, Mukundapur Kolkata, 700099 India.

出版信息

Indian J Thorac Cardiovasc Surg. 2023 May;39(3):319-321. doi: 10.1007/s12055-023-01492-w. Epub 2023 Feb 21.

DOI:10.1007/s12055-023-01492-w
PMID:37124604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10140207/
Abstract

VEST III trial is the largest randomized controlled trial to date to evaluate the role of external stents on late graft failure. In this study, an external stent was applied to vein grafts and compared with another unsupported vein graft in the same patient. The groups were compared for overall graft patency and intimal hyperplasia. Patent vein grafts were further assessed and graded based on the Fitzgibbon patency scale. This review discusses the strengths and weaknesses of the trial.

摘要

VEST III试验是迄今为止评估外部支架对晚期移植物失败作用的最大规模随机对照试验。在本研究中，对静脉移植物应用外部支架，并与同一患者的另一未支撑静脉移植物进行比较。比较两组的总体移植物通畅率和内膜增生情况。根据菲茨吉本通畅量表对通畅的静脉移植物进一步评估和分级。本综述讨论了该试验的优缺点。

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1
VEST III trial - should we support the vein grafts?VEST III试验——我们应该支持静脉移植物吗？
Indian J Thorac Cardiovasc Surg. 2023 May;39(3):319-321. doi: 10.1007/s12055-023-01492-w. Epub 2023 Feb 21.
2
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本文引用的文献

1
The evolving evidence base for coronary artery bypass grafting and arterial grafting in 2021: How to improve vein graft patency.2021年冠状动脉旁路移植术和动脉移植术不断发展的证据基础：如何提高静脉移植物通畅率。
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2
External stenting and disease progression in saphenous vein grafts two years after coronary artery bypass grafting: A multicenter randomized trial.冠状动脉旁路移植术后 2 年，体外支架和隐静脉移植物病变进展：一项多中心随机试验。
J Thorac Cardiovasc Surg. 2022 Nov;164(5):1532-1541.e2. doi: 10.1016/j.jtcvs.2021.03.120. Epub 2021 Apr 21.
3
Commentary: External stenting of saphenous vein grafts-reinVESTing to achieve best returns in coronary artery bypass grafting.
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4
Long-term performance of an external stent for saphenous vein grafts: the VEST IV trial.隐静脉移植血管外部支架的长期性能：VEST IV试验
J Cardiothorac Surg. 2018 Nov 19;13(1):117. doi: 10.1186/s13019-018-0803-9.
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Eight-year follow-up of the Clopidogrel After Surgery for Coronary Artery Disease (CASCADE) trial.冠状动脉疾病手术后氯吡格雷（CASCADE）试验的 8 年随访结果。
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A prospective study of external stenting of saphenous vein grafts to the right coronary artery: the VEST II study.一项关于右冠状动脉大隐静脉移植血管体外支架置入术的前瞻性研究：VEST II研究
Eur J Cardiothorac Surg. 2017 May 1;51(5):952-958. doi: 10.1093/ejcts/ezw438.
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A Randomized Trial of External Stenting for Saphenous Vein Grafts in Coronary Artery Bypass Grafting.冠状动脉旁路移植术中隐静脉移植物外部支架置入的随机试验
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