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实验动物血清化学和血液学值的参考范围数据库。

Reference range data base for serum chemistry and hematology values in laboratory animals.

作者信息

Wolford S T, Schroer R A, Gohs F X, Gallo P P, Brodeck M, Falk H B, Ruhren R

出版信息

J Toxicol Environ Health. 1986;18(2):161-88. doi: 10.1080/15287398609530859.

Abstract

A reference range data base containing serum chemistry and hematology values on over 3000 animals is described. Data listed include the mean, standard deviation, and 10th and 90th percentiles for each of the following parameters. Serum chemistry: sodium, potassium, chloride, calcium, inorganic phosphorus, urea nitrogen, creatinine, total bilirubin, total protein, glucose, cholesterol, triglycerides, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase (monkey only), lactate dehydrogenase (dog only), and creatine kinase (dog only). Hematology: hematocrit, hemoglobin, red blood cells, reticulocytes, mean cell volume, mean cell hemoglobin, mean cell hemoglobin percent, platelets, white blood cells, neutrophils, eosinophils, basophils, lymphocytes, monocytes, and stabs. The species included are mouse, rat, hamster, rabbit, beagle dog, and cynomolgus monkey. The use of the reference ranges in routine computerized data collection is discussed.

摘要

描述了一个包含3000多种动物血清化学和血液学值的参考范围数据库。列出的数据包括以下每个参数的平均值、标准差以及第10和第90百分位数。血清化学指标:钠、钾、氯、钙、无机磷、尿素氮、肌酐、总胆红素、总蛋白、葡萄糖、胆固醇、甘油三酯、碱性磷酸酶、天冬氨酸转氨酶、丙氨酸转氨酶、γ-谷氨酰转移酶(仅猴子)、乳酸脱氢酶(仅狗)和肌酸激酶(仅狗)。血液学指标:血细胞比容、血红蛋白、红细胞、网织红细胞、平均细胞体积、平均细胞血红蛋白、平均细胞血红蛋白百分比、血小板、白细胞、中性粒细胞、嗜酸性粒细胞、嗜碱性粒细胞、淋巴细胞、单核细胞和杆状核细胞。所包括的物种有小鼠、大鼠、仓鼠、兔子、比格犬和食蟹猴。讨论了在常规计算机化数据收集中参考范围的使用。

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