Samet J, Hunt W C, Key C, Humble C G, Goodwin J S
JAMA. 1986 Jun 27;255(24):3385-90.
We used data on 22,899 cancer cases collected by the New Mexico Tumor Registry to examine the relationship between patient age and the use of potentially curative therapy for cancers of selected sites and acute leukemias. For cancers of most sites, either local or regional stage, the proportion of cases receiving potentially curative therapy declined with age. For local-stage cancers, the proportion not given any treatment increased with age. Overall mortality rates during the first year after diagnosis were much higher for local-stage cases without treatment than for those who received treatment. These data show that cancer therapy varies with age and suggest that decision making regarding therapy is influenced by the presence of other diseases.
我们使用了新墨西哥肿瘤登记处收集的22899例癌症病例数据,以研究患者年龄与特定部位癌症及急性白血病的潜在治愈性治疗使用之间的关系。对于大多数部位的癌症,无论是局部还是区域阶段,接受潜在治愈性治疗的病例比例都随年龄下降。对于局部阶段的癌症,未接受任何治疗的比例随年龄增加。诊断后第一年,未接受治疗的局部阶段病例的总体死亡率远高于接受治疗的病例。这些数据表明癌症治疗因年龄而异,并表明治疗决策受其他疾病的影响。