Xiang Xuejing, Luo Yuanyuan, Du Haibo, Ma Xiaojie
Department of Oncology, Affifiliated Hospital of North Sichuan Medical College, Nanchong, China.
Department of General Surgery, Guang 'an Hospital, West China Hospital, Sichuan University, Guangan, China.
Ear Nose Throat J. 2023 Apr 27:1455613231173452. doi: 10.1177/01455613231173452.
Synovial sarcoma (SS) is a rare malignant tumor with bidirectional differentiation potential in epithelial and mesenchymal tissues and is a more chemosensitive subtype of soft tissue sarcoma. It occurs around the synovial soft tissues of large joints of the extremities and rarely in the nasopharynx. We present a young man with recurrent left-sided nasal congestion with nosebleeds, confirmed by immunohistochemistry and cytogenetic examination as SS. SS is easily misdiagnosed, and the tumor should be considered in the differential diagnosis, with surgery combined with radiotherapy as the primary treatment option.
滑膜肉瘤(SS)是一种罕见的恶性肿瘤,具有上皮和间充质组织双向分化潜能,是软组织肉瘤中对化疗更敏感的亚型。它发生于四肢大关节的滑膜软组织周围,很少发生于鼻咽部。我们报告一名青年男性,反复出现左侧鼻塞伴鼻出血,经免疫组化和细胞遗传学检查确诊为滑膜肉瘤。滑膜肉瘤容易误诊,鉴别诊断时应考虑到该肿瘤,主要治疗选择为手术联合放疗。