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用于肿瘤成像的基于维生素的放射性药物。

Vitamin-based radiopharmaceuticals for tumor imaging.

机构信息

Department of Medical Services and Techniques, Usak University, Vocational School of Health Services, Usak, 64100, Turkey.

Department of Chemistry, Faculty of Science and Arts, Usak University, Usak, 64100, Turkey.

出版信息

Med Oncol. 2023 May 2;40(6):165. doi: 10.1007/s12032-023-02031-8.

Abstract

Advances in nuclear medicine, such as single photon emission computed tomography (SPECT) and positron emission tomography (PET), are among the most sensitive methods that can be used in diagnostic imaging and radionuclide therapy with higher efficiency and reduced toxicity benefits. In order to improve the success of treatment, it is also important to develop methods that can be used when lesions can be detected at the earliest stages. Vitamins are macromolecules that play a crucial role in numerous biological processes in both animals and humans. Escalating development of vitamin-based radiopharmaceuticals for application in the diagnosis and treatment of cancers. In this review, we aimed to discuss about recent research utilizing radio-labeled vitamins for targeted tumor imaging.

摘要

核医学的进展,如单光子发射计算机断层扫描(SPECT)和正电子发射断层扫描(PET),是在诊断成像和放射性核素治疗中使用的最敏感的方法之一,具有更高的效率和降低毒性的益处。为了提高治疗的成功率,开发能够在最早阶段检测到病变的方法也很重要。维生素是在动物和人类的许多生物过程中发挥关键作用的大分子。基于维生素的放射性药物的开发不断发展,用于癌症的诊断和治疗。在这篇综述中,我们旨在讨论最近利用放射性标记的维生素进行靶向肿瘤成像的研究。

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