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输尿管支架相关的脊椎椎间盘炎。

Ureteric stent associated spondylodiscitis.

机构信息

Frimley Park Hospital NHS Foundation Trust, Frimley, UK

Frimley Park Hospital NHS Foundation Trust, Frimley, UK.

出版信息

BMJ Case Rep. 2023 May 2;16(5):e252457. doi: 10.1136/bcr-2022-252457.

DOI:10.1136/bcr-2022-252457
Abstract

This case report describes a clinical presentation of spondylodiscitis, following an emergency ureteric stent placement for an infected and obstructed kidney in a woman in her late 70s who presented with right flank pain, raised inflammatory markers and an acute kidney injury. Non-contrast CT kidney, ureters and bladder (KUB) revealed a 9 mm obstructing stone and prompt decompression with a JJ stent was performed. Although the urine culture showed no growth at first, an extended spectrum beta-lactamase was found in a subsequent urine culture after discharge. Postoperatively, the patient described a novel, worsening lower back pain and had persistently elevated inflammatory markers. An MRI revealed spondylodiscitis of L5/S1, for which she was treated with a 6-week course of antibiotics, and she has made a good but slow recovery. This case shows the unusual finding of spondylodiscitis postureteric stent placement and clinicians should be aware of this rare complication.

摘要

本病例报告描述了一位 70 多岁女性在因感染和梗阻性肾病行紧急输尿管支架置入术后出现的脊椎炎表现。该女性因右侧腰痛、炎症标志物升高和急性肾损伤就诊。非增强 CT 肾、输尿管和膀胱(KUB)显示有 9mm 梗阻性结石,立即行 JJ 支架置入术以进行快速减压。尽管最初尿液培养未见生长,但在出院后的后续尿液培养中发现了一种扩展谱β-内酰胺酶。术后,患者描述了一种新的、加重的下腰痛,且炎症标志物持续升高。MRI 显示 L5/S1 的脊椎炎,因此她接受了 6 周的抗生素治疗,目前恢复良好但较为缓慢。本病例显示了一种不常见的输尿管支架置入术后脊椎炎表现,临床医生应意识到这种罕见的并发症。

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本文引用的文献

1
Ureteral stent complications - experience on 50,000 procedures.输尿管支架并发症 - 50000 例经验。
J Med Life. 2021 Nov-Dec;14(6):769-775. doi: 10.25122/jml-2021-0352.
2
Global Trends in Incidence and Burden of Urolithiasis from 1990 to 2019: An Analysis of Global Burden of Disease Study Data.1990年至2019年全球尿石症发病率和负担趋势:全球疾病负担研究数据分析
Eur Urol Open Sci. 2022 Jan 3;35:37-46. doi: 10.1016/j.euros.2021.10.008. eCollection 2022 Jan.
3
Is primary ureteroscopy an alternative to emergency stenting in terms of quality and cost?
就质量和成本而言,原发性输尿管镜检查能否替代急诊支架置入术?
Cent European J Urol. 2021;74(3):446-450. doi: 10.5173/ceju.2021.0029.R1. Epub 2021 Jun 2.
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Spinal Infections: An Update.脊柱感染:最新进展
Microorganisms. 2020 Mar 27;8(4):476. doi: 10.3390/microorganisms8040476.
5
The health and cost burden of antibiotic resistant and susceptible Escherichia coli bacteraemia in the English hospital setting: A national retrospective cohort study.在英国医院环境中,耐抗生素和敏感的大肠杆菌菌血症的健康和费用负担:一项全国性回顾性队列研究。
PLoS One. 2019 Sep 10;14(9):e0221944. doi: 10.1371/journal.pone.0221944. eCollection 2019.
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Evaluation of Challenges in Diagnosis of Spontaneous Subacute Pyogenic Spondylodiscitis in Immunocompetent Patients: Experiences from a Tertiary Care Center.免疫功能正常患者自发性亚急性化脓性脊椎椎间盘炎诊断挑战的评估:来自三级医疗中心的经验
Asian Spine J. 2019 Apr 2;13(4):621-629. doi: 10.31616/asj.2018.0220. Print 2019 Aug.
7
Ureteral stent-associated infection and sepsis: pathogenesis and prevention: a review.输尿管支架相关感染与脓毒症:发病机制与预防:综述
Biofouling. 2019 Jan;35(1):117-127. doi: 10.1080/08927014.2018.1562549. Epub 2019 Feb 8.
8
Prevention and management of urosepsis triggered by ureteroscopy.输尿管镜检查引发的尿脓毒症的预防与管理
Res Rep Urol. 2018 Jul 5;10:43-49. doi: 10.2147/RRU.S128071. eCollection 2018.
9
Burden of Urolithiasis: Trends in Prevalence, Treatments, and Costs.尿石症负担:患病率、治疗方法和费用的趋势。
Eur Urol Focus. 2017 Feb;3(1):18-26. doi: 10.1016/j.euf.2017.04.001. Epub 2017 Apr 24.
10
Spinal infections in older people: an analysis of demographics, presenting features, microbiology and outcomes.老年人脊柱感染:人口统计学、临床表现、微生物学及预后分析
Intern Med J. 2017 Feb;47(2):182-188. doi: 10.1111/imj.13300.