Alanzi Ahemd, Adeel Shahid, Hakmi Samah, AlDerazi Amer
Anesthesia and Critical Care, King Hamad University Hospital, Muharraq, BHR.
Surgery - General and Bariatric Surgery, Salmaniya Medical Complex, Manama, BHR.
Cureus. 2023 Mar 31;15(3):e36975. doi: 10.7759/cureus.36975. eCollection 2023 Mar.
Background Appendicitis is a common clinical problem that has multifactorial etiologies. Accounting for almost 1 million hospital days per year, it poses serious health hazards. If not treated on time, it may burst. Surgical intervention is the best option in such cases. Prophylactic use of antibiotics has been shown to reduce post-operative infections. Methodology This prospective observational study aimed to evaluate the adherence to the antibiotic prophylaxis guidelines for appendectomy in patients admitted to the surgical department at Salmanyia Medical Complex in Bahrain from January to August 2020. From the electronic records of these patients, information was extracted and evaluated regarding demographic data, the type of antibiotics given for prophylaxis, the timing of the administration of the antibiotics, and any alternative antibiotic given based on local hospital guidelines. Results The current study revealed that the majority of the patients (98%, N=273) admitted to the Salmanyia Medical Complex, Bahrain, were not administered the antibiotics within the prescribed time (30-60 minutes) as per hospital guidelines. Also, the antibiotics administered for prophylaxis prior to the appendectomy procedure were not according to the guidelines, i.e., Cefazolin 1g with Metronidazole 500 mg. Out of a total of 278 patients included in the study, none were administered the right choice as provided by the local guidelines. Second, 1.8% of patients (5 out of 278) were not administered any antibiotics for prophylaxis prior to the surgical procedure for appendicitis. Conclusion The study concluded that most patients were not administered antibiotics according to the local guidelines of the hospital.
阑尾炎是一个常见的临床问题,病因具有多因素性。每年导致近100万个住院日,构成严重的健康危害。若不及时治疗,可能会破裂。在这种情况下,手术干预是最佳选择。预防性使用抗生素已被证明可减少术后感染。
这项前瞻性观察性研究旨在评估2020年1月至8月在巴林萨尔马尼亚医疗中心外科住院的阑尾炎患者对阑尾切除术抗生素预防指南的遵循情况。从这些患者的电子记录中提取并评估有关人口统计学数据、预防性使用的抗生素类型、抗生素给药时间以及根据当地医院指南给予的任何替代抗生素的信息。
当前研究显示,巴林萨尔马尼亚医疗中心的大多数患者(98%,N = 273)未按照医院指南在规定时间(30 - 60分钟)内使用抗生素。此外,阑尾切除术前预防性使用的抗生素不符合指南,即头孢唑林1g加甲硝唑500mg。在纳入研究的总共278名患者中,没有一人按照当地指南使用正确的药物。其次,1.8%的患者(278名中的5名)在阑尾炎手术前未接受任何预防性抗生素治疗。
该研究得出结论,大多数患者未按照医院的当地指南使用抗生素。