Lafreniere R, Moskowitz L B, Ketcham A S
J Surg Oncol. 1986 Feb;31(2):113-9. doi: 10.1002/jso.2930310208.
Pathological curiosities have always fascinated the surgical community, and management of breast cancer by the physician has, at times, revealed such rarities. A recent case of squamous cell carcinoma in a clear fluid breast cyst has prompted a review of our experience with this rare pathology, and allowed us to make the following statements: We propose that squamous cell carcinoma of the breast arises from ductal metaplasia. When the T.N.M. system is applied to the squamous cell lesion, the apparent poor prognosis that it is believed to carry may not be so apparent. If no other primaries are identified after extensive metastatic work-up, surgical therapy consisting of total mastectomy with complete axillary dissection, is very effective in local control of tumor progress. Nodal status will indicate the need for additional modalities of therapy.
病理学上的奇闻轶事一直吸引着外科界，而医生对乳腺癌的治疗有时也揭示出了此类罕见病例。近期一例发生在清亮液性乳腺囊肿内的鳞状细胞癌病例促使我们回顾了我们在这种罕见病理学方面的经验，并得出以下结论：我们认为乳腺鳞状细胞癌起源于导管化生。当将T.N.M.系统应用于鳞状细胞病变时，人们认为其预后较差这一点可能并不那么明显。如果在广泛的转移检查后未发现其他原发灶，那么包括全乳切除加腋窝淋巴结清扫的手术治疗对局部控制肿瘤进展非常有效。淋巴结状态将表明是否需要额外的治疗方式。
