Lamela M, Cadavid I, Calleja J M
J Ethnopharmacol. 1986 Feb;15(2):153-60. doi: 10.1016/0378-8741(86)90152-2.
Ether extracts of Lythrum salicaria stems and flowers exhibited significant hypoglycemic activity in rats with glucose- and epinephrine-induced hyperglycemia when the animals were given oral doses equivalent to 10 g/kg of starting material. These extracts were also found to be active in alloxan- and streptozotocin-diabetic rats and alloxan-diabetic mice. While both stem and flower extracts reduced the elevated gamma-glutamyl transpeptidase activity induced by streptozotocin in rats, only the stem extract reduced the elevated lactic dehydrogenase activity also seen. The flower extract clearly accentuated the elevated levels of aspartate aminotransferase induced by streptozotocin.
当给大鼠口服相当于10克/千克起始原料的剂量时，柳叶菜茎和花的乙醚提取物对葡萄糖和肾上腺素诱导的高血糖大鼠表现出显著的降血糖活性。这些提取物在四氧嘧啶和链脲佐菌素诱导的糖尿病大鼠以及四氧嘧啶糖尿病小鼠中也被发现具有活性。虽然茎提取物和花提取物都降低了链脲佐菌素诱导的大鼠γ-谷氨酰转肽酶活性升高，但只有茎提取物降低了同时出现的乳酸脱氢酶活性升高。花提取物明显加剧了链脲佐菌素诱导的天冬氨酸转氨酶水平升高。
