Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, and Department of Medical Biotechnologies, University of Siena, Italy.
Rheumatology Unit, Department of Medical Sciences, University of Ferrara and Azienda Ospedaliero-Universitaria S. Anna, Ferrara, Italy.
Clin Exp Rheumatol. 2023 May;41(5):997-1008. doi: 10.55563/clinexprheumatol/4uc7e8. Epub 2023 May 3.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide range of clinical manifestations and a relapsing-remitting course. New data regarding pathogenic pathways, biomarkers and clinical manifestations of SLE are emerging, and new drugs and therapeutic protocols have been proposed to improve the control of disease activity. Furthermore, new insights into comorbidities and reproductive health in SLE patients are constantly emerging.This annual review aims to summarise the most relevant data on SLE that was published in 2022.
系统性红斑狼疮(SLE)是一种慢性自身免疫性疾病,具有广泛的临床表现和反复发作的病程。关于 SLE 的发病机制途径、生物标志物和临床表现的新数据不断涌现,并且提出了新的药物和治疗方案来改善疾病活动的控制。此外,关于 SLE 患者合并症和生殖健康的新见解也在不断涌现。本年度综述旨在总结 2022 年发表的关于 SLE 的最相关数据。