Adinolfi Antonella, Valentini Eleonora, Calabresi Emanuele, Tesei Giulia, Signorini Viola, Barsotti Simone, Tani Chiara
Department of Rheumatology, Policlinico Le Scotte, University of Siena, Italy.
Rheumatology Unit, University of Perugia, Italy.
Clin Exp Rheumatol. 2016 Jul-Aug;34(4):569-74. Epub 2016 Jul 14.
Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with a highly variable course and prognosis. The management of the disease is still a clinical challenge for the treating physicians as many aspects regarding the disease pathogenesis, clinical picture and outcomes remain to be elucidated. New and interesting data are emerging; here the recent literature on SLE pathogenesis, clinical and laboratory aspects, as well as treatments and comorbidities, are reviewed and the main findings summarised in order to provide a bird's eye on the relevant papers on these topics.
系统性红斑狼疮（SLE）是一种病程和预后高度多变的全身性自身免疫性疾病。对于治疗医生而言，该疾病的管理仍是一项临床挑战，因为关于疾病发病机制、临床表现和结局的许多方面仍有待阐明。新的有趣数据不断涌现；在此，对近期关于SLE发病机制、临床和实验室方面以及治疗和合并症的文献进行综述，并总结主要发现，以便对这些主题的相关论文有一个全面的了解。
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