Fukuda Y
Nihon Geka Gakkai Zasshi. 1986 Mar;87(3):324-35.
Plasma CEA (P-CEA) in 50 cases with bile duct carcinoma and tissue CEA (T-CEA) detected by PAP method in 46 resected cases with carcinoma were examined. The mean level of P-CEA was 4.4 +/- 0.6 ng/ml and the positive rate was 68%. It was considered that a factor of vessel invasion was closely related to the increasing factor of P-CEA. Concerning the relationship between P-CEA and prognosis of the patient, the level of P-CEA seemed to be useful as a parameter of recurrence of carcinoma during the follow up periods. T-CEA in the cancerous lesion was positive in 76%. There were no relations between the histology of the carcinoma and the ability to produce CEA. Conclusively, the histological type invasion of the carcinoma was detected clearly and easily by using the PAP method for T-CEA. To examine the T-CEA in the resected margin seemed to be useful as an additional diagnostic method for carcinoma in the residual bile duct.
检测了50例胆管癌患者的血浆癌胚抗原（P-CEA），并对46例手术切除的癌组织采用PAP法检测组织癌胚抗原（T-CEA）。P-CEA的平均水平为4.4±0.6 ng/ml，阳性率为68%。认为血管侵犯因素与P-CEA升高因素密切相关。关于P-CEA与患者预后的关系，P-CEA水平似乎可作为随访期间癌复发的一个参数。癌灶中的T-CEA阳性率为76%。癌的组织学类型与产生CEA的能力之间无相关性。总之，采用PAP法检测T-CEA能清晰、简便地检测出癌的组织学类型浸润情况。检测切除边缘的T-CEA似乎可作为残余胆管癌的一种辅助诊断方法。
