Mutagenicity of 1,2-dibromo-3-chloropropane (DBCP) in the mouse spot test.
作者信息
Sasaki Y F, Imanishi H, Watanabe M, Sekiguchi A, Moriya M, Shirasu Y, Tutikawa K
出版信息
Mutat Res. 1986 Jun;174(2):145-7. doi: 10.1016/0165-7992(86)90106-5.
PMID:3713732
Abstract
The spot test with 1,2-dibromo-3-chloropropane (DBCP) was carried out using male PW and female C57BL/6 mice. DBCP induced recessive colour spots in offspring with a significantly high frequency of 2.9%, showing that this chemical is mutagenic for somatic cells of mice in vivo.
摘要
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