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Multi-omics and case-control analyses identify immunoglobulin M as a tumour-derived serum biomarker of ocular adnexal extranodal marginal zone lymphoma.

作者信息

Shi Jiahao, Zhou Min, Zhou Xiaowen, Jia Shichong, Liu Zhen, Zhao Yi, Shi Jiahui, Song Xin, Wang Yefei, Jia Renbing, Zhou Yixiong, Fan Xianqun

机构信息

Department of Ophthalmology, Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital, Shanghai, P. R. China.

Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, P. R. China.

出版信息

Clin Transl Med. 2023 May;13(5):e1259. doi: 10.1002/ctm2.1259.

DOI:10.1002/ctm2.1259
PMID:37138540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10157263/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/9856693a3533/CTM2-13-e1259-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/eb64a74741db/CTM2-13-e1259-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/16da52939c8a/CTM2-13-e1259-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/790372fa57cf/CTM2-13-e1259-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/9856693a3533/CTM2-13-e1259-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/eb64a74741db/CTM2-13-e1259-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/16da52939c8a/CTM2-13-e1259-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/790372fa57cf/CTM2-13-e1259-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/875b/10157263/9856693a3533/CTM2-13-e1259-g001.jpg

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Multi-omics and case-control analyses identify immunoglobulin M as a tumour-derived serum biomarker of ocular adnexal extranodal marginal zone lymphoma.多组学和病例对照分析确定免疫球蛋白M为眼附属器结外边缘区淋巴瘤的肿瘤源性血清生物标志物。
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本文引用的文献

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Proteotranscriptomics of ocular adnexal B-cell lymphoma reveals an oncogenic role of alternative splicing and identifies a diagnostic marker.眼附属器 B 细胞淋巴瘤的蛋白质组转录组学研究揭示了选择性剪接的致癌作用,并鉴定出一个诊断标志物。
J Exp Clin Cancer Res. 2022 Jul 30;41(1):234. doi: 10.1186/s13046-022-02445-8.
2
Machine learning for multi-omics data integration in cancer.用于癌症多组学数据整合的机器学习
iScience. 2022 Jan 22;25(2):103798. doi: 10.1016/j.isci.2022.103798. eCollection 2022 Feb 18.
3
Determinants of Serum Immunoglobulin Levels: A Systematic Review and Meta-Analysis.
血清免疫球蛋白水平的决定因素:系统评价和荟萃分析。
Front Immunol. 2021 Apr 7;12:664526. doi: 10.3389/fimmu.2021.664526. eCollection 2021.
4
Using machine learning approaches for multi-omics data analysis: A review.使用机器学习方法进行多组学数据分析:综述
Biotechnol Adv. 2021 Jul-Aug;49:107739. doi: 10.1016/j.biotechadv.2021.107739. Epub 2021 Mar 29.
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Machine learning for precision medicine.机器学习与精准医学
Genome. 2021 Apr;64(4):416-425. doi: 10.1139/gen-2020-0131. Epub 2020 Oct 22.
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Improving diagnostic performance of differentiating ocular adnexal lymphoma and idiopathic orbital inflammation using intravoxel incoherent motion diffusion-weighted MRI.采用体素内不相干运动扩散加权 MRI 提高眼眶附属器淋巴瘤和特发性眼眶炎症的诊断性能。
Eur J Radiol. 2020 Sep;130:109191. doi: 10.1016/j.ejrad.2020.109191. Epub 2020 Jul 25.
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International multicentre retrospective cohort study of ocular adnexal marginal zone B-cell lymphoma.眼附属器黏膜相关边缘区 B 细胞淋巴瘤的国际多中心回顾性队列研究。
Br J Ophthalmol. 2020 Mar;104(3):357-362. doi: 10.1136/bjophthalmol-2019-314008. Epub 2019 Jun 8.
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Front Immunol. 2018 Oct 2;9:2242. doi: 10.3389/fimmu.2018.02242. eCollection 2018.
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