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来自一名全新世个体的古基因组支持阿拉斯加东南部的基因连续性。

A paleogenome from a Holocene individual supports genetic continuity in Southeast Alaska.

作者信息

Aqil Alber, Gill Stephanie, Gokcumen Omer, Malhi Ripan S, Reese Esther Aaltséen, Smith Jane L, Heaton Timothy T, Lindqvist Charlotte

机构信息

Department of Biological Sciences, University at Buffalo, Buffalo, NY 14260, USA.

Department of Anthropology and Carl R. Woese Institute for Genomic Biology, University of Illinois Urbana-Champaign, Urbana, IL 61801, USA.

出版信息

iScience. 2023 Apr 8;26(5):106581. doi: 10.1016/j.isci.2023.106581. eCollection 2023 May 19.

DOI:10.1016/j.isci.2023.106581
PMID:37138779
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10149335/
Abstract

Many specifics of the population histories of the Indigenous peoples of North America remain contentious owing to a dearth of physical evidence. Only few ancient human genomes have been recovered from the Pacific Northwest Coast, a region increasingly supported as a coastal migration route for the initial peopling of the Americas. Here, we report paleogenomic data from the remains of a ∼3,000-year-old female individual from Southeast Alaska, named (). Our results demonstrate at least 3,000 years of matrilineal genetic continuity in Southeast Alaska, and that is most closely related to ancient and present-day northern Pacific Northwest Coast Indigenous Americans. We find no evidence of Paleo-Inuit (represented by ) ancestry in present-day or ancient Pacific Northwest peoples. Instead, our analyses suggest the genome harbors Northern Native American ancestry. This study sheds further light on the human population history of the northern Pacific Northwest Coast.

摘要

由于实物证据匮乏,北美原住民人口历史的许多细节仍存在争议。从太平洋西北海岸仅找回了少数古代人类基因组,该地区越来越多地被认为是美洲最初人类定居的沿海迁徙路线。在此,我们报告了来自阿拉斯加东南部一名约3000年前女性个体(名为 )遗骸的古基因组数据。我们的结果表明,阿拉斯加东南部至少有3000年的母系遗传连续性,并且 与古代和当今北太平洋西北海岸的美洲原住民关系最为密切。我们在当今或古代太平洋西北海岸的人群中没有发现古因纽特人(以 为代表)血统的证据。相反,我们的分析表明, 基因组含有北美北部原住民的血统。这项研究进一步揭示了北太平洋西北海岸的人类人口历史。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/e37054d445d0/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/90adf7dad509/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/d92356bb27ea/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/c0c0d74fefad/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/4f95e29b031b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/c5d10d04fe93/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/5ae5968c914b/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/9bfc6e9f9285/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/e37054d445d0/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/90adf7dad509/fx1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/d92356bb27ea/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/c0c0d74fefad/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/4f95e29b031b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/c5d10d04fe93/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/5ae5968c914b/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/9bfc6e9f9285/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd77/10149335/e37054d445d0/gr7.jpg

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