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三种草药配方对登革热媒介的比较研究。

Comparative study of three herbal formulations against dengue vectors .

作者信息

Alyahya Hanan S

机构信息

Department of Biology Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

出版信息

Saudi J Biol Sci. 2023 Jun;30(6):103651. doi: 10.1016/j.sjbs.2023.103651. Epub 2023 Apr 14.

Abstract

The efficacy of three formulations (i.e., natural lavender crude, essential oil, and gel) extracted from was tested against vectors of the epidemic dengue virus, , to evaluate their larvicidal activity effect. The ethanolic extract of the lavender crude was prepared using a rotary evaporator, while the other extracts, such as essential oil and gel, were obtained from iHerb, a supplier of medicinal herbs in the US. The mortality rate of larvae was evaluated 24 h after exposure. Larvicidal activity of the lavender crude was 91% mortality at 150 ppm, 94% for essential oil at a concentration of 3000 ppm, and 97% for lavender gel at a 1000 ppm. Natural lavender crude was one of the most promising extracts tested against . larvae, with lethal concentrations at LC and LC of 76.4 and 174.5 ppm post-treatment. The essential oil had the least effect on mosquito larvae, with LC and LC reaching 1814.8 and 3381.9 ppm, respectively. The lavender gel was moderately effective against larvae, with LC and LC values reaching 416.3 and 987.7 ppm after exposure. The occurrence of morphological abnormalities in the larvae treated with the three compounds, in turn, resulted in an incomplete life cycle. Therefore, our results indicated that natural lavender crude displayed the highest larvicidal activity against larvae, followed by gel and essential oil. Thus, this study concluded that lavender crude is an effective, eco-friendly compound that can be used as an alternative to chemical products to control vector-borne epidemic diseases.

摘要

对从薰衣草中提取的三种制剂(即天然薰衣草粗提物、精油和凝胶)针对登革热流行病毒的传播媒介进行了测试,以评估它们的杀幼虫活性效果。薰衣草粗提物的乙醇提取物使用旋转蒸发仪制备,而其他提取物,如精油和凝胶,则购自美国草药供应商iHerb。暴露24小时后评估幼虫的死亡率。薰衣草粗提物在150 ppm时的杀幼虫活性导致91%的死亡率,精油在3000 ppm浓度下为94%,薰衣草凝胶在1000 ppm时为97%。天然薰衣草粗提物是针对登革热病毒幼虫测试的最有前景的提取物之一,处理后其LC₅₀和LC₉₀的致死浓度分别为76.4和174.5 ppm。精油对蚊虫幼虫的影响最小,其LC₅₀和LC₉₀分别达到1814.8和3381.9 ppm。薰衣草凝胶对登革热病毒幼虫有中等效果,暴露后LC₅₀和LC₉₀值分别达到416.3和987.7 ppm。用这三种化合物处理的幼虫出现形态异常,进而导致生命周期不完整。因此,我们的结果表明,天然薰衣草粗提物对登革热病毒幼虫表现出最高的杀幼虫活性,其次是凝胶和精油。因此,本研究得出结论,薰衣草粗提物是一种有效、环保的化合物,可作为化学产品的替代品用于控制媒介传播的流行病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bda/10149404/7b0911dd926d/gr1.jpg

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