Department of Cardiology and Cardiac Rehabilitation, Anhui Wannan Rehabilitation Hospital, The Fifth People's Hospital of Wuhu, Wuhu, Anhui Province, China.
Eur Rev Med Pharmacol Sci. 2023 Apr;27(8):3406-3419. doi: 10.26355/eurrev_202304_32111.
The purpose of this study was to explore the effect of a new cardiac rehabilitation mode on the cardiac function, mental state and quality of life of patients with acute myocardial infarction (AMI) after percutaneous coronary intervention (PCI) with atorvastatin calcium tablets.
A total of 120 AMI patients treated with PCI and atorvastatin calcium tablets between January 2018 and January 2019 were recruited and assigned 1:1 to receive either novel cardiac rehabilitation (experimental group) or conventional cardiac rehabilitation (control group), with 60 cases in each group. Outcome measures for evaluating the effectiveness of the novel cardiac rehabilitation mode included cardiac function indices, 6 minutes walking distance test (6MWD), adverse mental state, quality of life (QOL), incidence of complications, and satisfaction on recovery.
Patients after novel cardiac rehabilitation care showed better cardiac function than those with conventional care (p<0.001). Patients had longer 6MWD and higher QOL after novel cardiac rehabilitation care vs. those given conventional care (p<0.001). The lower scores of adverse mental state in the experimental group suggested a better psychological status of patients after receiving novel cardiac rehabilitation care when compared with those with conventional care (p<0.001). Patients were also more satisfied with the novel modality of cardiac rehabilitation care than with conventional care (p<0.05).
The new cardiac rehabilitation mode can effectively improve the cardiac function of AMI patients after PCI plus atorvastatin calcium tablets, enhance their cardiac function, mitigate their negative emotions, and reduce the risk of complications. Further trials are required prior to clinical promotion.
本研究旨在探讨阿托伐他汀钙联合经皮冠状动脉介入治疗（PCI）后新型心脏康复模式对急性心肌梗死（AMI）患者心脏功能、精神状态和生活质量的影响。
选取 2018 年 1 月至 2019 年 1 月期间采用阿托伐他汀钙联合 PCI 治疗的 120 例 AMI 患者，按 1:1 随机分为新型心脏康复组（实验组）和常规心脏康复组（对照组），每组 60 例。评估新型心脏康复模式有效性的结局指标包括心脏功能指标、6 分钟步行距离试验（6MWD）、不良精神状态、生活质量（QOL）、并发症发生率和康复满意度。
新型心脏康复护理组患者的心脏功能优于常规护理组（p<0.001）。新型心脏康复护理组患者的 6MWD 更长，QOL 更高（p<0.001）。与常规护理组相比，实验组不良心理状态评分较低，表明患者接受新型心脏康复护理后的心理状态更好（p<0.001）。患者对新型心脏康复护理的满意度也高于常规护理（p<0.05）。
新型心脏康复模式可有效改善 PCI 加阿托伐他汀钙治疗后的 AMI 患者心脏功能，增强其心功能，减轻其负性情绪，降低并发症风险。需要进一步的临床试验来推广这种新型的心脏康复模式。
