Neefe L I, Tuazon C U, Cardella T A, Sheagren J N
Am J Med Sci. 1979 Jan-Feb;277(1):99-110. doi: 10.1097/00000441-197901000-00013.
An adult drug abuser with endocarditis due to a group II Staphylococcus aureus developed the staphylococcal scalded skin syndrome (SSSS). Studies of the patient's immune function found cell-mediated immunity (CMI) to be essentially normal; thus, previous suggestions that deficient CMI is required in adults who develop SSSS seem unfounded. Pathogenesis, diagnosis, and therapy of SSSS and its differentiation from drug-induced hypersensitivity reaction are discussed in detail.
一名因Ⅱ组金黄色葡萄球菌感染患心内膜炎的成年药物滥用者出现了葡萄球菌烫伤样皮肤综合征（SSSS）。对该患者免疫功能的研究发现其细胞介导免疫（CMI）基本正常；因此，先前认为发生SSSS的成年人需要CMI缺陷的观点似乎没有依据。本文详细讨论了SSSS的发病机制、诊断和治疗以及它与药物性过敏反应的鉴别。
