Department of General Medicine, Government Vellore Medical College, Vellore, India.
Department of General Medicine, Governement Omandurar Medical College, Chennai, India.
Ir J Med Sci. 2023 Dec;192(6):2793-2799. doi: 10.1007/s11845-023-03376-9. Epub 2023 May 4.
Diabetic neuropathy diagnosis involves invasive procedures like nerve biopsy and nerve conduction studies which are seldom available at rural health centers. The Ipswich Touch Test (IpTT) is one test that can be performed by the caregiver and it's simple to perform.
This study was aimed to compare the validity of the IpTT and 10gm-SMWF (10-gm Semmes-Weinstein mono-filament) test with the vibration perception threshold (VPT) using biothesiometer.
Two hundred patients with type 2 diabetes, between the age of 30 and 50 years, were included in the study. The neuropathy assessment was performed by biothesiometer, 10gm-SMWF test, and IpTT. Taking VPT(> 25 V) as the gold standard; the sensitivity and specificity of IpTT and 10gm-SMWF are calculated and compared to each other.
On comparing with the VPT, the 10gm-SMWF test had a sensitivity of 94.7% and specificity of 85.7%, and the IpTT had a sensitivity of 91.9% and specificity of 85.7%. 10gm-SMWF test (Kappa value 0.733) had better agreement with VPT than IpTT (Kappa value 0.675). On Spearman's correlation, the 10gm-SMWF test and the IpTT had r values of 0.738 and 0.686 respectively (P = 0.000).
10gm-SMWFis a better test to diagnose neuropathy than the IpTT; but in the absence of 10gm-SMWFs, the IpTT is an ideal alternative. IpTT can be performed in a bedside or chairside setting in the absence of a professional health care provider who can screen patients for neuropathy and alert the physician of an impending complication where amputation can be avoided.
糖尿病周围神经病变的诊断需要进行神经活检和神经传导研究等有创操作,而这些操作在农村卫生中心很少开展。Ipswich 触觉测试(IpTT)是一种可以由护理人员进行的测试,操作简单。
本研究旨在比较 Ipswich 触觉测试(IpTT)和 10gm-SMWF(10 克单丝丝感觉检查仪)测试与振动感觉阈值(VPT)测量仪检测的有效性。
纳入了 200 名年龄在 30 至 50 岁之间的 2 型糖尿病患者。使用振动感觉阈值(VPT)测量仪对神经病学进行评估,包括 10gm-SMWF 测试和 Ipswich 触觉测试。以 VPT(>25V)为金标准;计算并比较 IpsTT 和 10gm-SMWF 的灵敏度和特异性。
与 VPT 相比,10gm-SMWF 测试的灵敏度为 94.7%,特异性为 85.7%,IpTT 的灵敏度为 91.9%,特异性为 85.7%。10gm-SMWF 测试(Kappa 值为 0.733)与 VPT 的一致性优于 IpsTT(Kappa 值为 0.675)。在 Spearman 相关分析中,10gm-SMWF 测试和 IpsTT 的 r 值分别为 0.738 和 0.686(P=0.000)。
与 IpsTT 相比,10gm-SMWF 是诊断周围神经病变的更好测试方法;但在缺乏 10gm-SMWF 的情况下,IpsTT 是理想的替代方法。在没有专业医疗保健提供者的情况下,可在床边或椅子旁进行 IpsTT,以筛查周围神经病变患者,并提醒医生即将发生并发症,从而避免截肢。