2019年冠状病毒病大流行对偏头痛患者的影响。
The impact of the COVID-19 pandemic on patients with migraine.
作者信息
Hrytsenko Olena, Kopchak Oksana, Kozyk Marko, Strubchevska Kateryna
机构信息
Department of Neurology, Psychiatry and Physical Rehabilitation, Private Higher Educational Establishment "Kyiv Medical University", Kyiv, Ukraine.
Internal Medicine Resident, Corewell Health William Beaumont University Hospital, Royal Oak, MI, USA.
出版信息
SAGE Open Med. 2023 Apr 28;11:20503121231170726. doi: 10.1177/20503121231170726. eCollection 2023.
OBJECTIVES
The aim of our work was to assess the impact of the COVID-19 pandemic and quarantine measures on migraine patients in regards to the activity of the disease, the psycho-emotional background of the patients and their quality of life.
METHODS
his study included 133 patients with established diagnosis of migraine. All study participants were divided into two clinical groups: A-patients with chronic and episodic forms of migraine, who had a history of positive PCR test for COVID-19, and B-patients with chronic and episodic forms of migraine who did not have a history of coronavirus disease.
RESULTS
We detected increase in the number of antimigraine medication ( = 0.04), frequency of headache attacks ( = 0.01), and the psycho-emotional state deterioration (increase in the Hamilton anxiety scale score) ( = 0.002) in patients after recovery from the coronavirus disease. There was no significant difference in the headache's intensity according to the VAS scale ( = 0.51) as well as in the dynamics of the Beck depression scale score ( = 0.09) before and after the COVID-19 infection.
CONCLUSION
Patients with a history of migraine who recovered from COVID-19 showed increased frequency of migraine headache attacks and anxiety.
目的
我们的工作旨在评估新冠疫情及隔离措施对偏头痛患者疾病活动度、心理情绪背景及其生活质量的影响。
方法
本研究纳入了133例确诊偏头痛患者。所有研究参与者被分为两个临床组：A组为慢性和发作性偏头痛患者，有新冠病毒核酸检测阳性史；B组为慢性和发作性偏头痛患者，无新冠病毒疾病史。
结果
我们发现，新冠病毒感染康复后的患者，抗偏头痛药物使用量增加（P = 0.04）、头痛发作频率增加（P = 0.01）以及心理情绪状态恶化（汉密尔顿焦虑量表评分增加）（P = 0.002）。根据视觉模拟量表（VAS），头痛强度在新冠病毒感染前后无显著差异（P = 0.51），贝克抑郁量表评分变化也无显著差异（P = 0.09）。
结论
从新冠病毒感染中康复的偏头痛病史患者，偏头痛头痛发作频率和焦虑增加。
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