School of Psychology, The University of Sydney, Camperdown, NSW, Australia.
School of Psychology and Translational Health Research Institute, Western Sydney University, Sydney, NSW, Australia.
Child Neuropsychol. 2024 Apr;30(3):425-443. doi: 10.1080/09297049.2023.2205633. Epub 2023 May 5.
To (i) determine whether accelerated long-term forgetting (ALF) can be found using standardized verbal memory test materials in children with genetic generalized epilepsy (GGE) and temporal lobe epilepsy (TLE), and (ii) to establish whether ALF is impacted by executive skills and repeat testing over long delays. One hundred and twenty-three children aged 8 to 16, (28 with GGE, 23 with TLE, and 72 typically developing; TD) completed a battery of standardized tests assessing executive functioning and memory for two stories. Stories were recalled immediately and after a 30-min delay. To examine whether repeat testing impacts long-term forgetting, one story was tested via free recall at 1-day and 2-weeks, and the other at 2-weeks only. Recognition was then tested for both stories at 2-weeks. Children with epilepsy recalled fewer story details, both immediately and after 30-min relative to TD children. Compared to TD children, the GGE group, but not the TLE group, showed ALF, having significantly poorer recall of the story tested only at the longest delay. Poor executive skills were significantly correlated with ALF for children with epilepsy. Standard story memory materials can detect ALF in children with epilepsy when administered over long delays. Our findings suggest that (i) ALF is related to poor executive skills in children with epilepsy, and (ii) repeated testing may ameliorate ALF in some children.
（一）确定是否可以使用标准化的言语记忆测试材料在遗传性全面性癫痫（GGE）和颞叶癫痫（TLE）儿童中发现加速的长期遗忘（ALF），以及（二）确定ALF是否受执行技能和长时间延迟后的重复测试的影响。123 名 8 至 16 岁的儿童（28 名 GGE、23 名 TLE 和 72 名正常发育；TD）完成了一系列标准化测试，评估执行功能和两个故事的记忆。故事立即和 30 分钟后延迟进行回忆。为了检查重复测试是否会影响长期遗忘，一个故事通过自由回忆在 1 天和 2 周进行测试，另一个故事仅在 2 周时进行测试。然后在 2 周时对两个故事进行识别测试。癫痫儿童的故事细节回忆较少，无论是立即回忆还是 30 分钟后回忆都比 TD 儿童少。与 TD 儿童相比，GGE 组而非 TLE 组表现出 ALF，仅在最长延迟时对测试的故事的回忆明显较差。执行技能差与癫痫儿童的 ALF 显著相关。标准故事记忆材料可在长时间延迟后检测到癫痫儿童的 ALF。我们的发现表明：（一）ALF 与癫痫儿童的执行技能差有关，（二）重复测试可能会改善某些儿童的 ALF。
