[Interaction of micro-dispersed forms of anionites and surface-active agents with serum albumin].

The interaction of serum albumin with microdispersed forms of anion-exchange resins AV-16 GS and AV-17 I (USSR), obtained by mechanochemical destruction of polymers, and with low-molecular weight anionic (oleic acid, sulfonol) and cationic (cetazol, catamine) surfactants was being studied. Catamine and cetazol as well as microdispersions of anion-exchange resins are able to precipitate 90% of protein from the equilibrium solution, the content of protein in the initial solution being constant and equal to 6.5 mg/ml. Studies on the equilibrium in the system serum albumin--microdispersions of anion-exchange resins in the presence of ionogenic surfactants revealed that cationic surfactants are able to increase the amount of the precipitated protein, while in the presence of anionic surfactants the interactions between the protein macromolecules and microdispersions of polyelectrolytes become much weaker.