Tottori Regional Center of The Japan Environment and Children's Study, Faculty of Medicine, Tottori University, Tottori, Japan.
Division of Health Administration and Promotion, Department of Social Medicine, Faculty of Medicine, Tottori University, Tottori, Japan.
Sci Rep. 2023 May 5;13(1):7363. doi: 10.1038/s41598-023-34547-4.
No studies showed the association between weight-loss behaviors before pregnancy and postpartum depression (PPD). We analyzed data from the nation-wide birth cohort study, the Japan Environment and Children's Study. Self-administrated questionnaires answered by 62,446 women was analyzed using logistic regression analysis. PPD was assessed using the Edinburgh Postnatal Depression Scale at 1 month after delivery. Women using at least one weight-loss method had higher risk of PPD than women using no weight-loss methods [women without antenatal psychological distress according to Kessler 6-Item Psychological Distress score: adjusted odds ratio (aOR) 1.318, 95% confidence interval (CI) 1.246-1.394; women with antenatal psychological distress: aOR 1.250, 95% CI 0.999-1.565]. Using extremely unhealthy weight-loss methods was associated with PPD compared with no use of each weight-loss method (vomiting after eating: aOR 1.743, 95% CI 1.465-2.065; smoking: aOR 1.432, 95% CI 1.287-1.591; taking diet pills: aOR 1.308, 95% CI 1.122-1.520). The association between weight-loss behaviors and PPD varied according to pre-pregnancy BMI. In normal-weight women, the weight-loss method score, which indicates the degree of weight-loss method use, was associated with PPD. These results indicate using weight-loss methods before pregnancy is associated with an increased risk of PPD in Japanese women.
没有研究表明怀孕前的减肥行为与产后抑郁症（PPD）之间存在关联。我们分析了全国性出生队列研究——日本环境与儿童研究的数据。通过逻辑回归分析，对 62446 名女性的自我管理问卷数据进行了分析。产后 1 个月使用爱丁堡产后抑郁量表评估 PPD。与不使用减肥方法的女性相比，使用至少一种减肥方法的女性患 PPD 的风险更高[根据 Kessler 6 项心理困扰评分无产前心理困扰的女性：调整后的优势比（aOR）1.318，95%置信区间（CI）1.246-1.394；有产前心理困扰的女性：aOR 1.250，95%CI 0.999-1.565]。与不使用每种减肥方法相比，使用极不健康的减肥方法与 PPD 相关（进食后呕吐：aOR 1.743，95%CI 1.465-2.065；吸烟：aOR 1.432，95%CI 1.287-1.591；服用减肥药：aOR 1.308，95%CI 1.122-1.520）。减肥行为与 PPD 之间的关联因孕前 BMI 而异。在正常体重女性中，减肥方法评分（表示减肥方法使用程度）与 PPD 相关。这些结果表明，日本女性怀孕前使用减肥方法与 PPD 风险增加有关。
