[考地米松的慢性毒性试验]
[Chronic toxicity testing of Cordemcura].
作者信息
Zschorn E M, Stade K, Janowski K
出版信息
Pharmazie. 1986 Mar;41(3):210-1.
PMID:3714799
Abstract
Transient thrombocytopenia and increased HK and Hb values was found after chronic administration of Cordemcura to Wistar rats. In the high dosage group stomach and intestinal bleedings were seen macroscopically, but no histological changes were found.
摘要
对Wistar大鼠长期给予考地米松后，发现有短暂性血小板减少以及己糖激酶（HK）和血红蛋白（Hb）值升高。在高剂量组，肉眼可见胃肠道出血，但未发现组织学变化。
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