Department of Radiology, Chi Mei Medical Center, Liouying, Tainan 73657, Taiwan.
Department of Medical Imaging and Radiological Science, Central Taiwan University of Science and Technology, Taichung 40601, Taiwan.
Radiat Prot Dosimetry. 2023 Jun 23;199(10):1120-1128. doi: 10.1093/rpd/ncad145.
The self-attenuation of a patient's body is an important factor in nuclear medicine for designing radiation shielding. Taiwanese reference man (TRM) and Taiwanese reference woman (TRW) were constructed to simulate the body dose rate constant and the effective body absorption factor for 18F-FDG, 131I-NaI and 99mTc-MIBI using the Monte Carlo technique. For TRM, the maximum body dose rate constants for 18F-FDG, 131I-NaI and 99mTc-MIBI were 1.26 × 10-1, 4.89 × 10-2 and 1.76 × 10-2 mSv-m2/GBq-h, respectively, at heights of 110, 110 and 100 cm. For TRW, the results were 1.23 × 10-1, 4.75 × 10-2 and 1.68 × 10-2 mSv-m2/GBq-h at heights of 100, 100 and 90 cm. The effective body absorption factors were 32.6, 36.7 and 46.2% for TRM and 34.2, 38.5 and 48.6% for TRW. Regional reference phantoms along with the derived body dose rate constant and effective body absorption factor should be used for determining regulatory secondary standards in nuclear medicine.
患者身体的自衰减是核医学中设计辐射屏蔽的一个重要因素。为了使用蒙特卡罗技术模拟 18F-FDG、131I-NaI 和 99mTc-MIBI 的体剂量率常数和有效体吸收因子,构建了台湾参考人(TRM)和台湾参考女性(TRW)。对于 TRM,18F-FDG、131I-NaI 和 99mTc-MIBI 的最大体剂量率常数分别为 1.26×10-1、4.89×10-2 和 1.76×10-2 mSv-m2/GBq-h,高度分别为 110、110 和 100 cm。对于 TRW,结果分别为 1.23×10-1、4.75×10-2 和 1.68×10-2 mSv-m2/GBq-h,高度分别为 100、100 和 90 cm。TRM 的有效体吸收因子分别为 32.6%、36.7%和 46.2%,TRW 的有效体吸收因子分别为 34.2%、38.5%和 48.6%。应使用区域参考体模以及推导的体剂量率常数和有效体吸收因子来确定核医学中的监管次级标准。