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未能通过固定时间为1分钟的水供应时间表来证明定时诱导的食欲亢进。

Failure to demonstrate schedule-induced hyperphagia with a fixed time 1-minute water delivery schedule.

作者信息

Campbell K I, Oei T P

出版信息

Physiol Behav. 1986;36(5):839-44. doi: 10.1016/0031-9384(86)90440-3.

DOI:10.1016/0031-9384(86)90440-3
PMID:3714859
Abstract

The reduction of an animal's body weight to 80% of its Free Feeding Weight (FFW) is purported to be an important factor in the generation of schedule-induced behaviour. However, the importance of this factor in schedule-induced hyperphagia is unclear. Experimental studies in schedule-induced hyperphagia reported conflicting results. The aim of the present series of five experiments was to clarify the several conflicting factors in the generation of schedule-induced hyperphagia. Rats reduced to 80% FFW by water restriction and on a Fixed Time (FT) 1-min water delivery schedule showed that body weight reduction, water delivery schedule, size and distance of pellets, and order of schedule presentation were not important factors in the generation of schedule-induced hyperphagia. The failure of the present series of experiments to demonstrate schedule-induced hyperphagia suggests that this behaviour may be a specific class of schedule-induced behaviour that can only be demonstrated under the Bellingham, Wayner and Barone experimental paradigm.

摘要

将动物体重降至其自由进食体重(FFW)的80%被认为是产生定时诱导行为的一个重要因素。然而,该因素在定时诱导性多食症中的重要性尚不清楚。关于定时诱导性多食症的实验研究报告了相互矛盾的结果。本系列五个实验的目的是厘清在定时诱导性多食症产生过程中几个相互矛盾的因素。通过限水将大鼠体重降至FFW的80%,并采用固定时间(FT)1分钟供水时间表,结果表明体重减轻、供水时间表、食丸大小和距离以及时间表呈现顺序并非定时诱导性多食症产生的重要因素。本系列实验未能证明定时诱导性多食症,这表明这种行为可能是一类特定的定时诱导行为,只能在贝灵汉、韦纳和巴龙实验范式下才能得到证明。

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