The Department of Psychiatry, Yale School of Medicine, New Haven, CT 06511, USA.
The Department of Psychiatry, Yale School of Medicine, New Haven, CT 06511, USA.
Psychiatr Clin North Am. 2023 Jun;46(2):349-358. doi: 10.1016/j.psc.2023.02.006. Epub 2023 Mar 15.
This article reviews the role of psychotherapy in management of treatment-resistant depression (TRD). Meta-analyses of randomized trials show that psychotherapy has a positive therapeutic benefit in TRD. There is less evidence that one type of psychotherapy approach is superior to another. However, more trials have examined cognitive-based therapies than other forms of psychotherapy. Also reviewed is the potential combination of psychotherapy modalities and medication/somatic therapies as an approach to TRD. There is significant interest in ways that psychotherapy modalities could be combined with medication/somatic therapies to harness a state of enhanced neural plasticity and improve longer-term outcomes in mood disorders.
本文回顾了心理治疗在治疗抵抗性抑郁症（TRD）管理中的作用。随机试验的荟萃分析表明，心理治疗对 TRD 具有积极的治疗益处。有证据表明，一种心理治疗方法并不优于另一种。然而，更多的试验已经检查了基于认知的治疗方法，而不是其他形式的心理治疗。本文还回顾了心理治疗模式与药物/躯体治疗相结合作为治疗 TRD 的方法。人们非常关注心理治疗模式如何与药物/躯体治疗相结合，以利用增强的神经可塑性状态，并改善心境障碍的长期结果。
