Khojah Osama, Aljohani Sara, Aldahlawi Abdulaziz, Samkari Alaa, Alzahrani Moajeb
College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
King Abdullah International Medical Research Center, Jeddah, Saudi Arabia.
Surg Neurol Int. 2023 Apr 14;14:135. doi: 10.25259/SNI_131_2023. eCollection 2023.
Intraparenchymal meningioma is a rare entity of one of the most common brain tumors. It is challenging to diagnose preoperatively due to the vague clinical presentation and absence of stereotypical radiological features. These atypical features might mislead the differential to favor high-grade gliomas or brain metastasis.
We describe a case of a 46-year-old male who presented with vertigo, right-sided sensorineural hearing loss, and bilateral blurred vision. Contrast-enhanced magnetic resonance imaging of the brain revealed a large parieto-occipital contrast-enhanced mass with a multi-loculated cystic component and diffusion restriction but without dural attachment. A gross total reaction was achieved, and the histopathological results yielded a World Health Organization Grade I meningioma diagnosis. The patient exhibited no signs of recurrence after 2 years of follow-up.
Intraparenchymal meningiomas are difficult to identify without histopathological assessment. We emphasize the importance of considering this diagnosis when outlining an initial differential as it may direct management planning. Total surgical resection is the best treatment modality for such cases; however, radiotherapy is a valuable option. The prognosis of intraparenchymal meningiomas is generally favorable.
脑实质内脑膜瘤是最常见的脑肿瘤之一中的罕见类型。由于临床表现模糊且缺乏典型的影像学特征,术前诊断具有挑战性。这些非典型特征可能会使鉴别诊断偏向于高级别胶质瘤或脑转移瘤。
我们描述了一例46岁男性患者,其表现为眩晕、右侧感音神经性听力丧失和双侧视力模糊。脑部增强磁共振成像显示一个位于顶枕部的大的增强肿块,伴有多房囊性成分和弥散受限,但无硬脑膜附着。实现了全切,组织病理学结果诊断为世界卫生组织I级脑膜瘤。随访2年后,患者未出现复发迹象。
未经组织病理学评估,脑实质内脑膜瘤难以识别。我们强调在列出初步鉴别诊断时考虑这一诊断的重要性,因为它可能指导治疗计划。对于此类病例,手术全切是最佳治疗方式;然而,放疗也是一种有价值的选择。脑实质内脑膜瘤的预后总体良好。