Miles Daniel, Arbabi Cassra, McMackin Katherine, Tjaden Bruce, Schonefeld Sally, Baril Donald, Gupta NavYash, Gewertz Bruce, Azizzadeh Ali
Division of Vascular Surgery, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.
Division of Vascular and Endovascular Surgery, Cooper University Hospital, Camden, NJ.
J Vasc Surg Cases Innov Tech. 2022 Dec 10;9(2):101075. doi: 10.1016/j.jvscit.2022.11.012. eCollection 2023 Jun.
Persistent distal false lumen (FL) perfusion after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD) can lead to aneurysmal degeneration and an increased risk of rupture. We have presented our initial experience using a modified "candy-plug" (CP) technique for FL embolization.
From February 2021 to July 2022, we treated six patients using the modified CP technique. All the patients had undergone prior or simultaneous TEVAR for chronic TBAD with persistent FL perfusion and aneurysm expansion. Bilateral common femoral artery access was obtained, and intravascular ultrasound was used to confirm wire access in the true lumen (TL) and FL. A conformable TAG device (W.L. Gore & Associates, Flagstaff, AZ) was used in four cases and an Excluder aortic cuff (W.L. Gore & Associates) in two cases. The device was modified by placing a constraining "napkin-ring" suture through the middle segment of the device. Femoral sheaths were placed in the TL and FL. A standard TL TEVAR extension was performed at the level of the celiac artery (zone 5). Next, the CP device was advanced and deployed in the FL, distally aligning it with the TL device. An appropriately sized Amplatzer II plug (Abbot Vascular, Santa Clara, CA) was then deployed in the constrained segment of the modified stent graft. Completion angiography was performed to confirm successful FL embolization.
Technical success was defined as successful deployment of the CP device in the FL. The technical success rate was 100% (six of six patients). Clinical success was defined as the cessation of aneurysm growth on follow-up computed tomography angiography. No 30-day mortality, myocardial infarction, stroke, spinal cord ischemia, access site complications, or aortic-related reinterventions occurred. Surveillance imaging at a mean follow-up of 10 months confirmed clinical success (stable aneurysm size or shrinkage) for all five patients with follow-up data available.
The modified CP embolization technique is a promising solution for persistent distal FL perfusion after TEVAR for TBAD. Further investigation is required to determine the long-term durability of this technique as an adjunct to TEVAR to promote aortic remodeling.
B型主动脉夹层(TBAD)行胸主动脉腔内修复术(TEVAR)后,远端假腔(FL)持续灌注可导致动脉瘤样退变并增加破裂风险。我们展示了使用改良“糖果塞”(CP)技术进行FL栓塞的初步经验。
2021年2月至2022年7月,我们使用改良CP技术治疗了6例患者。所有患者均因慢性TBAD伴FL持续灌注和动脉瘤扩张而接受过前期或同期TEVAR治疗。经双侧股总动脉入路,使用血管内超声确认导丝进入真腔(TL)和FL。4例使用了顺应性TAG装置(W.L. Gore & Associates,弗拉格斯塔夫,亚利桑那州),2例使用了Excluder主动脉袖套(W.L. Gore & Associates)。通过在装置中段放置一个约束性“餐巾环”缝线对装置进行改良。在TL和FL中置入股动脉鞘。在腹腔干水平(5区)进行标准的TL TEVAR延伸。接下来,将CP装置推进并部署在FL中,使其在远端与TL装置对齐。然后在改良支架移植物的约束段部署尺寸合适的Amplatzer II封堵器(雅培血管,圣克拉拉,加利福尼亚州)。完成血管造影以确认FL栓塞成功。
技术成功定义为CP装置在FL中成功部署。技术成功率为100%(6例患者中的6例)。临床成功定义为随访计算机断层扫描血管造影显示动脉瘤生长停止。未发生30天死亡率、心肌梗死、中风、脊髓缺血、穿刺部位并发症或主动脉相关再次干预。平均随访10个月的监测影像证实,所有5例有随访数据的患者临床成功(动脉瘤大小稳定或缩小)。
改良CP栓塞技术是TBAD行TEVAR后远端FL持续灌注的一种有前景的解决方案。需要进一步研究以确定该技术作为TEVAR辅助手段促进主动脉重塑的长期耐久性。