Prayongrat Anussara, Kitpanit Sarin, Lertbutsayanukul Chawalit, Saikaew Pipop, Boonrueng Thirayu, Mekayarajjananonth Trakol, Vacharaksa Anjalee
Division of Radiation Oncology, Department of Radiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Department of Operative Dentistry and Endodontics, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Heliyon. 2023 Apr 17;9(5):e15374. doi: 10.1016/j.heliyon.2023.e15374. eCollection 2023 May.
The radiotherapy received by head and neck cancer patients commonly has adverse effects on oral tissue and the muscles of mastication. This short communication describes the digital fabrication of intraoral appliances for radiotherapy and muscle exercises.
Three patients diagnosed with tongue squamous carcinoma were treatment-planned for radiotherapy using different radiation techniques. The patients were referred for oral scanning and digital bite records, and the appliance was collaboratively designed by a radiation oncologist, dentist, and laboratory technician. The appliance covered the occlusal surface of the remaining teeth with a 1-mm engagement. The lingual plate was 2-mm below the occlusal plane, and extended 4-mm distally, and the jaws were opened by 20-mm. The appliances were printed overnight using a rigid and biocompatible 3D printing material.
Requiring minimal chair-time, the appliance was easily inserted and adjusted to comfortably fit in the mouth. The patients were trained to insert it themselves. The tongue was at a pre-determined position during daily radiotherapy, and the healthy tissues were separated from the radiation field. The patients had mild adverse effects on their oral mucosa. Additionally, the appliances were used for muscle exercises after the radiation courses to prevent trismus.
The interprofessional collaboration to fabricate customized intraoral appliances using digital workflow to maximize patients' benefits is feasible.
The use of intraoral appliances is potentially increased when the fabrication process is facilitated. Using an intraoral appliance precisely targets the tumor are for better treatment outcomes, and the healthy adjacent tissues will be preserved to maintain the patient's quality of life.
头颈癌患者接受的放射治疗通常会对口腔组织和咀嚼肌产生不良影响。本简短通讯描述了用于放射治疗和肌肉锻炼的口腔矫治器的数字化制作。
三名被诊断为舌鳞状细胞癌的患者采用不同的放射技术进行放射治疗计划。患者接受口腔扫描和数字化咬合记录,矫治器由放射肿瘤学家、牙医和实验室技术人员共同设计。矫治器以1毫米的贴合度覆盖剩余牙齿的咬合面。舌板位于咬合平面下方2毫米处,向远中延伸4毫米,颌间张开20毫米。矫治器使用刚性且生物相容的3D打印材料在夜间打印完成。
该矫治器所需的就诊时间最少,易于插入并调整以舒适地贴合口腔。患者接受了自行插入矫治器的培训。在每日放射治疗期间,舌头处于预定位置,健康组织与放射野分隔开。患者口腔黏膜出现轻度不良反应。此外,放射疗程结束后,使用矫治器进行肌肉锻炼以预防牙关紧闭。
通过跨专业协作,利用数字化工作流程制作定制的口腔矫治器以最大限度地提高患者受益是可行的。
当制作过程变得简便时,口腔矫治器的使用可能会增加。使用口腔矫治器能够精确靶向肿瘤区域以获得更好的治疗效果,同时保留健康的相邻组织以维持患者的生活质量。