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Efficacy and safety of dupilumab in bullous pemphigoid: a retrospective multicentric study of 36 patients.

作者信息

Moghadam Parna, Tancrede Emmanuelle, Bouaziz Jean-David, Kallout Julien, Bedane Christophe, Begon Edouard, Bourgault-Villada Isabelle, Calugareanu Andreea, Dereure Olivier, Jendoubi Fatma, Pham-Ledard Anne, Ingen-Housz-Oro Saskia, Picard-Dahan Catherine, Viguier Manuelle, Mahevas Thibault, Jachiet Marie, Charvet Estelle, Cassius Charles, Alexandre Marina, Lepelletier Clémence

机构信息

Dermatology Department, Saint-Louis Hospital, Paris, France.

出版信息

Br J Dermatol. 2023 Jul 17;189(2):244-246. doi: 10.1093/bjd/ljad136.

DOI:10.1093/bjd/ljad136
PMID:37155583
Abstract
摘要

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Efficacy and safety of dupilumab in bullous pemphigoid: a retrospective multicentric study of 36 patients.度普利尤单抗治疗大疱性类天疱疮的疗效和安全性:一项对36例患者的回顾性多中心研究。
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引用本文的文献

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IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes.大疱性类天疱疮中的IgG自身抗体在角质形成细胞中诱导致病性的依赖MyD88的促炎反应。
Nat Commun. 2025 Aug 6;16(1):7254. doi: 10.1038/s41467-025-62495-2.
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Cutaneous T Cell Lymphoma Following Dupilumab Therapy in Patients with Atopic Dermatitis: Clinical Review and Recommendations.度普利尤单抗治疗特应性皮炎患者后发生的皮肤T细胞淋巴瘤:临床综述与建议
Am J Clin Dermatol. 2025 May 26. doi: 10.1007/s40257-025-00955-7.
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Efficacy and safety of dupilumab in patients with moderate-to-severe bullous pemphigoid: a systematic review and meta-analysis.
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An Bras Dermatol. 2025 May-Jun;100(3):429-438. doi: 10.1016/j.abd.2024.08.008. Epub 2025 Mar 29.
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Bullous pemphigoid.大疱性类天疱疮
Nat Rev Dis Primers. 2025 Feb 20;11(1):12. doi: 10.1038/s41572-025-00595-5.
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Successful Treatment of Immune Checkpoint Inhibitor-Induced Bullous Pemphigoid with Omalizumab: A Case Report and Review of the Literature.奥马珠单抗成功治疗免疫检查点抑制剂诱导的大疱性类天疱疮:病例报告及文献综述
Clin Cosmet Investig Dermatol. 2024 Dec 14;17:2865-2874. doi: 10.2147/CCID.S487711. eCollection 2024.
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Use of dupilumab for recalcitrant bullous pemphigoid: A case report.度普利尤单抗用于治疗顽固性大疱性类天疱疮:一例报告。
SAGE Open Med Case Rep. 2024 Aug 22;12:2050313X241274855. doi: 10.1177/2050313X241274855. eCollection 2024.
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Fast Itch Relief during Dupilumab Predicts Clinical Efficacy in Bullous Pemphigoid: A Retrospective Cohort Study.度普利尤单抗治疗大疱性类天疱疮期间快速止痒可预测临床疗效:一项回顾性队列研究
Dermatology. 2024;240(5-6):694-701. doi: 10.1159/000540590. Epub 2024 Jul 29.
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Dupilumab effectively and rapidly treats bullous pemphigoid by inhibiting the activities of multiple cell types.度普利尤单抗通过抑制多种细胞类型的活性,有效且快速地治疗大疱性类天疱疮。
Front Immunol. 2023 Jul 27;14:1194088. doi: 10.3389/fimmu.2023.1194088. eCollection 2023.