单探针和共振四波混频实现新型关联光电子显微镜工作流程。
Single probes and resonant four-wave-mixing enabling novel correlative light electron microscopy workflow.
作者信息
Chen Long, He Chao
机构信息
Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.
Department of Engineering Science, University of Oxford, Oxford, OX1 3PJ, UK.
出版信息
Light Sci Appl. 2023 May 8;12(1):111. doi: 10.1038/s41377-023-01154-x.
Abstract
Correlative light electron microscopy prefers single probes with stable performance in both optical and electron microscopy. Now researchers have shown how to harness gold nanoparticles featuring exceptional photostability and four-wave-mixing nonlinearity to realize a new correlation imaging approach.
摘要
相关光电子显微镜术更青睐在光学显微镜和电子显微镜中均具有稳定性能的单一探针。如今，研究人员展示了如何利用具有卓越光稳定性和四波混频非线性特性的金纳米颗粒来实现一种新的关联成像方法。
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