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80岁以上患者的腹主动脉瘤切除术

Abdominal aortic aneurysm resection in patients more than 80 years old.

作者信息

Harris K A, Ameli F M, Lally M, Provan J L, Johnston K W, Goldberg M R, Walker P M

出版信息

Surg Gynecol Obstet. 1986 Jun;162(6):536-8.

PMID:3715686
Abstract

Improvement in anesthetic and surgical techniques has prompted a more aggressive approach to repair of abdominal aortic aneurysms in patients more than 80 years old. In order to determine if surgical treatment is justified, all of the patients who were more than 80 years old admitted to the hospital during the ten year period from 1974 to 1983 with the diagnosis of abdominal aortic aneurysm were reviewed. A total of 90 patients were available for analysis. The mortality of the 18 patients treated conservatively for ruptured aortic aneurysms was 100 per cent. Ten of the 27 patients operated upon for a ruptured aneurysm died yielding a mortality of 37 per cent. Eleven patients with symptomatic aneurysms had urgent repair with a mortality of 27 per cent. Only one of the 34 patients undergoing elective aneurysm repair died. There was no difference in the size of aneurysms among the groups. Although the ruptured aneurysms required more blood (10.2 +/- 3.7 units), there was no difference between the other two groups (symptomatic 4.5 +/- 3.1 units, elective 4.6 +/- 2.8 units). There was significantly fewer myocardial and renal complications in the elective group, although the sole death in this group was from myocardial infarction. Based upon these observations, we recommend aggressive elective therapy for selected patients who are more than 80 years of age with asymptomatic abdominal aortic aneurysms. Although the mortality is higher in those patients with symptomatic or ruptured aneurysms, it is not formidable, and therefore, repair should not be ruled out on the basis of age alone.

摘要

麻醉和外科技术的进步促使人们对80岁以上患者的腹主动脉瘤修复采取更积极的方法。为了确定手术治疗是否合理,我们回顾了1974年至1983年这十年间因腹主动脉瘤诊断入院的所有80岁以上患者。共有90例患者可供分析。18例因主动脉瘤破裂接受保守治疗的患者死亡率为100%。27例因动脉瘤破裂接受手术治疗的患者中有10例死亡,死亡率为37%。11例有症状的动脉瘤患者接受了紧急修复,死亡率为27%。34例接受择期动脉瘤修复的患者中只有1例死亡。各组间动脉瘤大小无差异。虽然破裂的动脉瘤需要更多的血液(10.2±3.7单位),但其他两组(有症状的4.5±3.1单位,择期的4.6±2.8单位)之间没有差异。择期组的心肌和肾脏并发症明显较少,尽管该组唯一的死亡是心肌梗死。基于这些观察结果,我们建议对80岁以上无症状腹主动脉瘤的特定患者进行积极的择期治疗。虽然有症状或破裂动脉瘤患者的死亡率较高,但并非不可接受,因此,不应仅基于年龄而排除修复治疗。

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