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多发性硬化症与神经胶质瘤并存。两例病例的临床及影像学描述

Coincidence of multiple sclerosis and glioma. Clinical and radiological remarks on two cases.

作者信息

Nahser H C, Vieregge P, Nau H E, Reinhardt V

出版信息

Surg Neurol. 1986 Jul;26(1):45-51. doi: 10.1016/0090-3019(86)90062-5.

DOI:10.1016/0090-3019(86)90062-5
PMID:3715699
Abstract

The clinical course and computed tomographic findings in two patients suffering from multiple sclerosis and coincidental gliomatous brain tumor are presented. Both diagnoses were proven by surgical biopsy; autopsy findings of one case are reported as well. Our results demonstrate that a differentiation of both diseases is not possible by computed tomography or by clinical data alone. Surgical biopsy to establish the diagnosis is indicated during the course of suspected multiple sclerosis when computed tomographic alterations and clinical signs of a space-occupying lesion last for some weeks.

摘要

本文报告了两名患有多发性硬化症并伴有巧合性脑胶质瘤的患者的临床病程及计算机断层扫描结果。两种诊断均经手术活检证实;还报告了其中一例的尸检结果。我们的结果表明,仅通过计算机断层扫描或临床数据无法区分这两种疾病。当计算机断层扫描改变及占位性病变的临床体征持续数周时,在疑似多发性硬化症的病程中,需进行手术活检以明确诊断。

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Coincidence of multiple sclerosis and glioma. Clinical and radiological remarks on two cases.多发性硬化症与神经胶质瘤并存。两例病例的临床及影像学描述
Surg Neurol. 1986 Jul;26(1):45-51. doi: 10.1016/0090-3019(86)90062-5.
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Concurrence of glioma and multiple sclerosis.胶质瘤与多发性硬化症并存。
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引用本文的文献

1
Concurrence of multiple sclerosis and brain tumors.多发性硬化症与脑肿瘤并发
Front Neurol. 2015 Mar 4;6:40. doi: 10.3389/fneur.2015.00040. eCollection 2015.
2
Genetic characterization of gliomas arising in patients with multiple sclerosis.多发性硬化症患者中发生的胶质瘤的遗传学特征。
J Neurooncol. 2012 Sep;109(2):261-72. doi: 10.1007/s11060-012-0888-2. Epub 2012 May 1.
3
The sad plight of multiple sclerosis research (low on fact, high on fiction): critical data to support it being a neurocristopathy.多发性硬化症研究的悲惨现状(事实少,虚构多):支持其为神经嵴病变的关键数据。
Inflammopharmacology. 2010 Dec;18(6):265-90. doi: 10.1007/s10787-010-0054-4. Epub 2010 Sep 24.
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Demyelinating diseases.脱髓鞘疾病
J Clin Pathol. 2006 Nov;59(11):1151-9. doi: 10.1136/jcp.2005.031195.
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Meningioma growth and interferon beta-1b treated multiple sclerosis: coincidence or relationship?
Neuroradiology. 2005 Jul;47(7):516-9. doi: 10.1007/s00234-005-1392-6. Epub 2005 Jun 25.
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Proton MR spectroscopy of tumefactive demyelinating lesions.肿瘤样脱髓鞘病变的质子磁共振波谱分析
AJNR Am J Neuroradiol. 2002 Sep;23(8):1378-86.