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[体外免疫吸附对特应性支气管哮喘病程的影响]

[Effect of extracorporeal immunosorption on the course of atopic bronchial asthma].

作者信息

Kazanbiev D N

出版信息

Ter Arkh. 1986;58(4):34-8.

PMID:3715753
Abstract

The paper is concerned with the results of assessment of the effect of immunosorption on a course of bronchial asthma in 10 patients with hypersensitifity to the domestic dust allergen and in 3 patients with hyperreactivity to the allergen of timothy pollen. Positive changes in the clinical status were also reflected in function of external respiration. A study of the humoral immunity revealed a decrease in the IgE level and an increase in the IgG level in a long-term postsorption period that might also provide for clinical remission of the disease. A decrease in skin hyperreactivity in the intracutaneous test was noted. A 6-month study of a course of the disease was indicative of a good therapeutic efficacy of the method of extracorporal immunosorption.

摘要

本文关注的是对10例对家用灰尘过敏原过敏和3例对梯牧草花粉过敏原反应过度的患者进行免疫吸附治疗支气管哮喘的效果评估结果。临床状况的积极变化也反映在外呼吸功能上。对体液免疫的研究表明,在长期吸附后阶段,IgE水平降低,IgG水平升高,这也可能促成疾病的临床缓解。皮内试验中皮肤反应过度性降低。对该疾病病程进行的为期6个月的研究表明,体外免疫吸附法具有良好的治疗效果。

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