4,6-Diamino-2-thiopyrimidine-based Cobalt Metal Organic Framework (Co-DAT-MOF): green, efficient, novel and reusable nanocatalyst for synthesis of multicomponent reactions.

In this study, Co-DAT-MOF powder was prepared via the solvothermal method using 4, 6-diamino-2-thiopyrimidine as the organic linker and Co(NO)·6HO. The synthesized catalysts are characterized using XRD, FT-IR, TGA, SEM, BET, NH-TPD, and ICP-OES techniques. SEM analysis clearly indicated the formation of nanosheet microspheres. NH-TPD-MS was employed as a means of identifying the various strengths of acid sites and their relative abundance in an attempt to explain the effect of the catalyst surface acid sites. We identified a new acidic feature in Co-DAT-MOF catalyst, related to the presence of desorption peaks in the NH-TPD profiles. The activity of Co-DAT-MOF catalyst for the synthesis of multicomponent reactions correlates with lewis acidity. In addition, Co-DAT-MOF exhibited excellent performance for the synthesis of pyrroloacridine-1(2H)-one and chromeno [2, 3- d] pyrimidin-8-amines, as well as good reusability and recyclability.